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How to get fromBuffalo to Sanibelby plane, bus (Flixbus, Greyhound), bus, train, taxi, or car

Find Transport to Sanibel

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There are 5 ways to get from Buffalo to Sanibel by plane, bus (Flixbus, Greyhound), bus, train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)plane plane BUF - RSW
    4h 56m
    $196–713

  2. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    36h 56m
    $316–487

  3. Bus, train, Amtrak Thruway, taxi

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Lakeland Amtrak Stationtrain train
    3. Take the bus from Lakeland to Fort Myers, FLbus bus
    4. Take the taxi from Fort Myers, FL to Sanibeltaxi taxi
    44h 57m

  4. Drive  1,343.8 mi

    1. Drive from Buffalo to Sanibelcar car 1,343.8 mi
    23h 24m
    $230–332

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Ft. Myers (RSW)plane plane ROC - RSW
    6h 17m
    $270–978

Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) flights

Calendar49Weekly Planes
Duration5h 31mAverage Duration
Ticket$124Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Sanibel.ExpandLaunch map view
  • Distance: 1,181.6 mi
  • Duration: 4h 56m

What companies run services between Buffalo, NY, USA and Sanibel, FL, USA?

JetBlue Airways, Southwest Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Buffalo to Sanibel via Newark Penn Station, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 36h 56m.

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