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How to get fromBuffalo to Sanibelby plane, bus (Greyhound, Flixbus), bus, train, taxi, or car

Find Transport to Sanibel

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There are 5 ways to get from Buffalo to Sanibel by plane, bus (Greyhound, Flixbus), bus, train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)plane plane BUF - RSW
    5h 11m
    $202–737

  2. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    40h 56m
    $322–490

  3. Bus, train, Amtrak Thruway, taxi

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Lakeland Amtrak Stationtrain train
    3. Take the bus from Lakeland to Fort Myers, FLbus bus
    4. Take the taxi from Fort Myers, FL to Sanibeltaxi taxi
    44h 57m

  4. Drive  1,343.8 mi

    1. Drive from Buffalo to Sanibelcar car 1,343.8 mi
    23h 24m
    $246–355

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Ft. Myers (RSW)plane plane ROC - RSW
    6h 27m
    $280–1,028

Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) flights

Calendar58Weekly Planes
Duration4h 53mAverage Duration
Ticket$134Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Sanibel.ExpandLaunch map view
  • Distance: 1,183.4 mi
  • Duration: 5h 11m

What companies run services between Buffalo, NY, USA and Sanibel, FL, USA?

JetBlue Airways, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Buffalo to Sanibel via Cleveland Bus Station, Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 40h 56m.

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