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How to get fromBuffalo to Sanibelby plane, bus (Greyhound, Flixbus), bus, train, taxi, or car

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There are 4 ways to get from Buffalo to Sanibel by plane, bus (Greyhound, Flixbus), bus, train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)plane plane BUF - RSW
    5h 10m
    $202–737

  2. Bus

    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    2. Take the bus from Youngstown Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    36h 51m
    $268–447

  3. Bus, train, Amtrak Thruway, taxi

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Lakeland Amtrak Stationtrain train
    3. Take the bus from Lakeland to Fort Myers, FLbus bus
    4. Take the taxi from Fort Myers, FL to Sanibeltaxi taxi
    44h 57m
    $511–1,128

  4. Drive  1,343.8 mi

    1. Drive from Buffalo to Sanibelcar car 1,343.8 mi
    23h 24m
    $246–355

Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) flights

Calendar45Weekly Planes
Duration4h 51mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Sanibel.ExpandLaunch map view
  • Distance: 1,183.4 mi
  • Duration: 5h 10m

What companies run services between Buffalo, NY, USA and Sanibel, FL, USA?

JetBlue Airways, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Buffalo, NY to Sanibel via Youngstown, OH, Youngstown Bus Stop, Washington Union Station, Orlando Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 36h 51m.

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