There are 6 ways to get from Buffalo to Southern Illinois University Carbondale by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Greyhound, Amtrak, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Williamson County Regional Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Williamson County Regional Airport (MWA)plane BUF - MWA
7h 23m$141–623Drive 746.2 mi
cheapest- Drive from Buffalo to Southern Illinois University Carbondalecar 746.2 mi
13h 1m$137–197Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to Carbondaletrain Saluki / ...
18h 41m$257–696Bus via Nashville
- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
22h 56m$140–272Fly to Lambert–St. Louis International Airport, bus
- Fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL)plane BUF - STL
- Take the bus from St. Louis to Carbondalebus
8h 54m$154–776Bus
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St. Louis to Carbondalebus
24h 46m$156–438
Buffalo Niagara International Airport (BUF) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Buffalo to Southern Illinois University Carbondale is to drive which costs $130 - $200 and takes 13h 1m.
The fastest way to get from Buffalo to Southern Illinois University Carbondale is to fly which takes 7h 23m and costs $140 - $650.
No, there is no direct bus from Buffalo to Southern Illinois University Carbondale station. However, there are services departing from Buffalo and arriving at Carbondale Intermodal Station via Cleveland Bus Station and Nashville Bus Station. The journey, including transfers, takes approximately 22h 56m.
No, there is no direct train from Buffalo to Southern Illinois University Carbondale. However, there are services departing from Buffalo and arriving at Carbondale via Buffalo Depew Station and Chicago Union Station. The journey, including transfers, takes approximately 18h 41m.
The distance between Buffalo and Southern Illinois University Carbondale is 676 miles. The road distance is 750.5 miles.
The best way to get from Buffalo to Southern Illinois University Carbondale without a car is to train which takes 18h 41m and costs $250 - $700.
It takes approximately 7h 23m to get from Buffalo to Southern Illinois University Carbondale, including transfers.
Buffalo to Southern Illinois University Carbondale bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Southern Illinois University Carbondale train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Southern Illinois University Carbondale is to fly which takes 7h 23m and costs $140 - $650. Alternatively, you can train, which costs $250 - $700 and takes 18h 41m, you could also bus via Nashville, which costs $140 - $280 and takes 22h 56m.
What companies run services between Buffalo, NY, USA and Southern Illinois University Carbondale, IL, USA?
American Airlines, United Airlines, and Corporate Flight Management Inc fly from Buffalo Niagara International Airport (BUF) to Williamson County Regional Airport (MWA) 4 times a day. Alternatively, you can take a train from Buffalo to Southern Illinois University Carbondale via Buffalo Depew Station, Chicago Union Station, and Carbondale in around 18h 41m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $130–700
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Baltimore
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $160–850
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 5h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $150–800
- Website
- united.com
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Washington Dulles
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $160–800
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $130–750
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $130–750
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $130–700
- Website
- contouraviation.com
Flights from Buffalo Niagara International Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $160–350
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $95–210
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- Greyhound
Bus from Cleveland Bus Station to Nashville Bus Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $90–180
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 55m
- Frequency
- 5 times a week
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from St. Louis to Carbondale
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–25
- Schedules at
- Flixbus USA
Bus from St. Louis to Carbondale
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–25
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
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More Questions & Answers
Buffalo to Southern Illinois University Carbondale bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Buffalo to Southern Illinois University Carbondale train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Southern Illinois University Carbondale is 751 miles. It takes approximately 13h 1m to drive from Buffalo to Southern Illinois University Carbondale.
There are 54+ hotels available in Southern Illinois University Carbondale.










