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How to get fromBuffalo to Spartanburgby plane, train (Amtrak), bus (Flixbus), car, train, or bus

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There are 6 ways to get from Buffalo to Spartanburg by plane, train (Amtrak), bus (Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP)plane plane BUF - GSP
    5h 25m
    $197–898

  2. Drive 709.2 mi

    cheapest
    1. Drive from Buffalo to Spartanburgcar car 709.2 mi
    12h 36m
    $130–187

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Spartanburg Stationtrain train Crescent
    23h 38m
    $363–736

  4. Bus

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus 2686 / ...
    2. Take the bus from New York Midtown to Spartanburgbus bus FlixBus N2471
    24h 14m
    $257–376

  5. Fly to Charlotte Douglas International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    6h 45m
    $160–834

  6. Bus via Newark

    1. Take the bus from Buffalo to Newarkbus bus Adt N813 / ...
    2. Take the bus from Newark Penn Station to Spartanburgbus bus Greyhound US0670
    25h 59m
    $227–473

Buffalo to Spartanburg by train (Amtrak)

Calendar7Weekly Trains
Duration23h 38mAverage Duration
Ticket$363Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Spartanburg.ExpandLaunch map view
  • Distance: 616 mi
  • Duration: 5h 25m

What companies run services between Buffalo, NY, USA and Spartanburg, SC, USA?

United Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a train from Buffalo to Spartanburg Station via Ny Moynihan Train Hall At Penn Station in around 23h 38m.

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