There are 5 ways to get from Buffalo to Syracuse by plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Catania–Fontanarossa Airport, bus
best- Fly from Buffalo Niagara International Airport (BUF) to Catania–Fontanarossa Airport (CTA)plane BUF - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
16h 48m€294–860Bus to Toronto Pearson International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Buffalo to Mississaugabus
- Fly from Toronto Pearson International Airport (YYZ) to Catania–Fontanarossa Airport (CTA)plane YYZ - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
16h 51m€345–661Bus to Rochester, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Catania–Fontanarossa Airport (CTA)plane ROC - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
19h 11m€388–1,144Train to Toronto Island Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Buffalo to Toronto Union Stationtrain
- Fly from Toronto Island Airport (YTZ) to Catania–Fontanarossa Airport (CTA)plane YTZ - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
20h 45m€487–1,005Fly Buffalo Niagara International Airport to Vincenzo Magliocco Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Vincenzo Magliocco Airport (CIY)plane BUF - CIY
- Take the train from Comiso to Siracusatrain
20h 40m€481–1,341
Buffalo Niagara International Airport (BUF) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Buffalo to Syracuse is to bus and fly which costs €340 - €700 and takes 16h 51m.
The fastest way to get from Buffalo to Syracuse is to fly and bus which takes 16h 48m and costs €290 - €900.
The distance between Buffalo and Syracuse is 7631 km.
It takes approximately 16h 48m to get from Buffalo to Syracuse, including transfers.
Syracuse is 6h ahead of Buffalo. It is currently 7:23 PM in Buffalo and 1:23 AM in Syracuse.
There are 3180+ hotels available in Syracuse.
What companies run services between Buffalo, NY, USA and Syracuse, Italy?
There is no direct connection from Buffalo to Syracuse. However, you can take the line 24 bus to Genesee Street & 4219 Genesee Street, walk to Buffalo Niagara International Airport (BUF) airport, fly to Catania–Fontanarossa Airport (CTA), walk to Catania Airport, then take the bus to Siracusa - v.le Scala Greca. Alternatively, you can take the bus to Mississauga, take the bus to City Centre Transit Terminal Platform A, walk to Square One, take the line 40 bus to Pearson International Airport Terminal 1, walk to Toronto Pearson International Airport (YYZ) airport, fly to Catania–Fontanarossa Airport (CTA), walk to Catania Airport, then take the bus to Siracusa - v.le Scala Greca.
- Website
- lufthansa.com
Flights from Buffalo Niagara International Airport to Catania–Fontanarossa Airport via Newark, Rome
- Ave. Duration
- 15h 35m
- When
- Every day
- Estimated price
- €260–950
Flights from Buffalo Niagara International Airport to Catania–Fontanarossa Airport via Boston, Munich
- Ave. Duration
- 15h 15m
- When
- Friday
- Estimated price
- €290–1,100
Flights from Toronto Pearson International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 10h 52m
- When
- Monday, Thursday, Saturday, Tuesday, Friday, and Sunday
- Estimated price
- €200–750
Flights from Toronto Pearson International Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 11h 37m
- When
- Every day
- Estimated price
- €210–850
Flights from Rochester to Catania–Fontanarossa Airport via Boston, Munich
- Ave. Duration
- 15h 15m
- When
- Friday
- Estimated price
- €360–1,300
Flights from Toronto Island Airport to Catania–Fontanarossa Airport via Montreal
- Ave. Duration
- 15h 10m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €220–850
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to Toronto Union Station
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- €25–150
- Website
- VIA Rail
- Escape
- €25–75
- Business
- €50–140
- Business Plus
- €60–150
- Economy
- €28–80
- Economy Plus
- €30–90
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide








