There are 3 ways to get from Buffalo to Syracuse, Ny by bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Buffalo to Syracuse, Ny by bus
Comparing Your Travel Options
The cheapest way to get from Buffalo to Syracuse, Ny is to drive which costs $25 - $40 and takes 2h 39m.
The fastest way to get from Buffalo to Syracuse, Ny is to bus which takes 2h 25m and costs $27 - $90.
Yes, there is a direct bus departing from Buffalo and arriving at Syracuse Bus Station station. Services depart hourly, and operate every day. The journey takes approximately 2h 25m.
Yes, there is a direct train departing from Buffalo and arriving at Syracuse Regional Transportation Center. Services depart four times a day, and operate every day. The journey takes approximately 2h 29m.
The distance between Buffalo and Syracuse, Ny is 150 miles. The road distance is 148.7 miles.
The best way to get from Buffalo to Syracuse, Ny without a car is to bus which takes 2h 25m and costs $27 - $90.
The bus from Buffalo to Syracuse Bus Station takes 2h 25m including transfers and departs hourly.
Buffalo to Syracuse, Ny bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Syracuse, Ny train services, operated by Amtrak, depart from Buffalo station.
The best way to get from Buffalo to Syracuse, Ny is to bus which takes 2h 25m and costs $27 - $90. Alternatively, you can train, which costs $40 - $190 and takes 2h 29m.
What companies run services between Buffalo, NY, USA and Syracuse, Ny, NY, USA?
Greyhound USA operates a bus from Buffalo to Syracuse Bus Station every 3 hours. Tickets cost $27–45 and the journey takes 2h 25m. Two other operators also service this route. Alternatively, Amtrak operates a train from Buffalo to Syracuse Regional Transportation Center 3 times a day. Tickets cost $80–130 and the journey takes 2h 29m. VIA Rail also services this route once daily.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 29m
- Frequency
- 3 times a day
- Estimated price
- $80–130
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–190
- Website
- VIA Rail
- Escape
- $40–110
- Business
- $70–180
- Business Plus
- $80–190
- Economy
- $40–120
- Economy Plus
- $45–120
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Every 3 hours
- Estimated price
- $27–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Every 2 hours
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Buffalo to Syracuse, Ny bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Buffalo to Syracuse, Ny train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Buffalo to Syracuse, Ny is 149 miles. It takes approximately 2h 39m to drive from Buffalo to Syracuse, Ny.
Book your Buffalo to Syracuse, Ny train tickets online with Omio.
Book your Buffalo to Syracuse, Ny bus tickets online with Omio and FlixBus.
There are 115+ hotels available in Syracuse, Ny.














