There are 4 ways to get from Buffalo to Twinsburg by train (Amtrak), bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Buffalo Depew Station to Cleveland Amtraktrain Lake Shore Limited
5h 7m$157–364Bus
cheapest- Take the bus from Buffalo to Akronbus Bsb 11
5h 40m$24–63Drive 195.7 mi
- Drive from Buffalo to Twinsburgcar 195.7 mi
3h 27m$36–52Fly
- Fly from Buffalo Niagara International Airport (BUF) to Cleveland-Hopkins International Airport (CLE)plane BUF - CLE
6h 51m$91–474
Buffalo Niagara International Airport (BUF) to Cleveland-Hopkins International Airport (CLE) flights
Comparing Your Travel Options
The cheapest way to get from Buffalo to Twinsburg is to bus which costs $24 - $65 and takes 5h 40m.
The fastest way to get from Buffalo to Twinsburg is to drive which takes 3h 27m and costs $35 - $55.
No, there is no direct bus from Buffalo to Twinsburg. However, there are services departing from Buffalo and arriving at Darrow Rd @ Giant Eagle via Robert K Pfaff Transit Center - Akron. The journey, including transfers, takes approximately 5h 40m.
No, there is no direct train from Buffalo to Twinsburg. However, there are services departing from Buffalo and arriving at Cleveland Amtrak via Buffalo Depew Station. The journey, including transfers, takes approximately 5h 7m.
The distance between Buffalo and Twinsburg is 216 miles. The road distance is 196.8 miles.
The best way to get from Buffalo to Twinsburg without a car is to train which takes 5h 7m and costs $150 - $370.
It takes approximately 5h 7m to get from Buffalo to Twinsburg, including transfers.
Buffalo to Twinsburg bus services, operated by Barons Bus, depart from Buffalo station.
Buffalo to Twinsburg train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Twinsburg is to train which takes 5h 7m and costs $150 - $370. Alternatively, you can bus, which costs $24 - $65 and takes 5h 40m, you could also fly, which costs $90 - $480 and takes 6h 51m.
What companies run services between Buffalo, NY, USA and Twinsburg, OH, USA?
Amtrak operates a train from Buffalo Depew Station to Cleveland Amtrak twice daily. Tickets cost $100–160 and the journey takes 3h 14m. Alternatively, Barons Bus operates a bus from Buffalo to Akron once daily. Tickets cost $22–65 and the journey takes 3h 55m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Philadelphia
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $95–550
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via New York La Guardia
- Ave. Duration
- 4h 6m
- When
- Monday to Saturday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Reagan Washington
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $90–550
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $70–450
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via New York La Guardia
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $90–550
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Newark
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $95–550
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Cleveland-Hopkins International Airport via Baltimore
- Ave. Duration
- 4h 26m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Cleveland Amtrak
- Ave. Duration
- 3h 14m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Buffalo to Akron
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $22–65
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Buffalo to Twinsburg bus services, operated by Barons Bus, arrive at Akron station.
Buffalo to Twinsburg train services, operated by Amtrak, arrive at Cleveland Amtrak station.
Yes, the driving distance between Buffalo to Twinsburg is 197 miles. It takes approximately 3h 27m to drive from Buffalo to Twinsburg.
There are 130+ hotels available in Twinsburg.