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How to get fromBuffalo to Walthamby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Buffalo to Waltham by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    3h 34m
    $81–442

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    11h 55m
    $71–137

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    13h 3m
    $143–461

  4. Drive 446.6 mi

    1. Drive from Buffalo to Walthamcar car 446.6 mi
    7h 46m
    $82–118

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    5h 6m
    $99–468

  6. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    14h 34m
    $80–139

Buffalo to Waltham by bus and foot (Greyhound)

Calendar7Weekly Services
Duration11h 55mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Waltham.ExpandLaunch map view
  • Distance: 420.9 mi
  • Duration: 3h 34m

What companies run services between Buffalo, NY, USA and Waltham, MA, USA?

American Airlines, JetBlue Airways, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS) every 4 hours. Alternatively, Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $65–140 and the journey takes 10h 5m.

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Need to know: Greyhound

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