There are 4 ways to get from Buffalo to Waterloo by bus (Greyhound, Amtrak), train (Amtrak), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo to Waterloo Amtrak Stationbus
8h 18m$75–133Drive 378.2 mi
cheapest- Drive from Buffalo to Waterloocar 378.2 mi
6h 46m$69–100Train (Amtrak)
- Take the train from Buffalo Depew Station to Waterloo Amtrak Stationtrain Lake Shore Limited
8h 29m$122–386Fly, taxi
- Fly from Buffalo Niagara International Airport (BUF) to Fort Wayne International Airport (FWA)plane BUF - FWA
- Take the taxi from Fort Wayne International Airport (FWA) to Waterlootaxi
6h 13m$171–578
Buffalo to Waterloo by bus
Questions & Answers
The cheapest way to get from Buffalo to Waterloo is to drive which costs $65 - $100 and takes 6h 46m.
The fastest way to get from Buffalo to Waterloo is to fly and taxi which takes 6h 13m and costs $170 - $600.
No, there is no direct bus from Buffalo to Waterloo station. However, there are services departing from Buffalo and arriving at Waterloo Amtrak Station via Cleveland Bus Station and Toledo. The journey, including transfers, takes approximately 8h 18m.
No, there is no direct train from Buffalo to Waterloo station. However, there are services departing from Buffalo and arriving at Waterloo Amtrak Station via Buffalo Depew Station. The journey, including transfers, takes approximately 8h 29m.
The distance between Buffalo and Waterloo is 393 miles. The road distance is 380.4 miles.
The best way to get from Buffalo to Waterloo without a car is to bus which takes 8h 18m and costs $70 - $140.
It takes approximately 8h 18m to get from Buffalo to Waterloo, including transfers.
Buffalo to Waterloo bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Waterloo train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Waterloo is to bus which takes 8h 18m and costs $70 - $140. Alternatively, you can train, which costs $120 - $390 and takes 8h 29m.
What companies run services between Buffalo, NY, USA and Waterloo, DeKalb County, IN, USA?
You can take a bus from Buffalo to Waterloo Amtrak Station via Cleveland Bus Station and Toledo in around 8h 18m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Waterloo Amtrak Station twice daily. Tickets cost $120–250 and the journey takes 7h 12m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Fort Wayne International Airport via Detroit
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Fort Wayne International Airport via Atlanta
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $150–700
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $95–500
Flights from Buffalo Niagara International Airport to Fort Wayne International Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Buffalo Niagara International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $95–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Waterloo Amtrak Station
- Ave. Duration
- 7h 12m
- Frequency
- Twice daily
- Estimated price
- $120–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Toledo to Waterloo Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Twice a week
- Estimated price
- $29–45
- Website
- https://www.amtrak.com/home.html
- Ave. Duration
- 49 min
- Estimated price
- $95–120
Deluxe Taxi Co
- Phone
- +1-260-426-8555
- Website
- deluxetaxifortwayne.net
Want to know more about travelling around United States
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More Questions & Answers
Buffalo to Waterloo bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Buffalo to Waterloo train services, operated by Amtrak, arrive at Waterloo Amtrak Station.
Yes, the driving distance between Buffalo to Waterloo is 380 miles. It takes approximately 6h 46m to drive from Buffalo to Waterloo.
Book your Buffalo to Waterloo train tickets online with Omio.
There are 16+ hotels available in Waterloo.







