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How to get fromBuffalo to West Lafayetteby plane, bus (Flixbus), train (Amtrak), car, bus, or train

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There are 8 ways to get from Buffalo to West Lafayette by plane, bus (Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Purdue University Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Purdue University Airport (LAF)plane plane BUF - LAF
    5h 33m
    $98–529

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Columbusbus bus Bsb 11
    2. Take the bus from Columbus to Lafayette Bus Stopbus bus FlixBus 2511 / ...
    13h 9m
    $72–148

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    15h 51m
    $207–565

  4. Drive 505.4 mi

    1. Drive from Buffalo to West Lafayettecar car 505.4 mi
    9h 5m
    $93–134

  5. Fly to Indianapolis, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    6h 50m
    $140–768

  6. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    6h 55m
    $173–443

  7. Fly to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 42m
    $142–546

  8. Bus via Reading

    1. Take the bus from Buffalo, NY to Woosterbus bus
    2. Take the bus from Wooster to Cincinnati, OHbus bus
    3. Take the bus from Cincinnati Bus Station to Lafayette Bus Stopbus bus
    16h 15m

Buffalo to West Lafayette by bus

Calendar14Weekly Buses
Duration13h 9mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to West Lafayette.ExpandLaunch map view
  • Distance: 469.6 mi
  • Duration: 5h 33m

What companies run services between Buffalo, NY, USA and West Lafayette, IN, USA?

United Airlines and American Airlines fly from Buffalo Niagara International Airport (BUF) to Purdue University Airport (LAF) 3 times a day. Alternatively, you can take a bus from Buffalo to Lafayette Bus Stop via Columbus, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 13h 9m.

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