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How to get fromBuffalo to West Lafayetteby plane, bus (Flixbus), train (Amtrak), car, bus, shuttle, train, or bus (Greyhound)

Find Transport to West Lafayette

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There are 8 ways to get from Buffalo to West Lafayette by plane, bus (Flixbus), train (Amtrak), car, bus, shuttle, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Purdue University Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Purdue University Airport (LAF)plane plane BUF - LAF
    7h 13m
    $68–403

  2. Bus (Flixbus)

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Lafayette Bus Stopbus bus FlixBus 2511 / ...
    12h 20m
    $84–129

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    15h 51m
    $161–517

  4. Drive  505.7 mi

    1. Drive from Buffalo to West Lafayettecar car 505.7 mi
    9h 5m
    $93–134

  5. Fly to Indianapolis, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 21m
    $115–592

  6. Fly to Chicago O'Hare International Airport, shuttle

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take a shuttle bus from O'Hare International Terminal 2 to West Lafayette, INshuttle bus
    7h 59m
    $203–363

  7. Fly to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    7h 59m
    $193–392

  8. Bus via Indianapolis

    1. Take the bus from Buffalo to Columbusbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus bus
    14h 45m
    $73–141

Buffalo to West Lafayette by bus (Flixbus)

Calendar6Weekly Buses
Duration12h 20mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to West Lafayette.ExpandLaunch map view
  • Distance: 471.4 mi
  • Duration: 7h 13m

What companies run services between Buffalo, NY, USA and West Lafayette, IN, USA?

United Airlines and American Airlines fly from Buffalo Niagara International Airport (BUF) to Purdue University Airport (LAF) every 4 hours. Alternatively, you can take a bus from Buffalo to Lafayette Bus Stop via Columbus in around 12h 20m.

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