Rome2Rio

How to get fromBuffalo to West Lafayetteby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), bus, shuttle, or train

Find Transport to West Lafayette

See all options

There are 8 ways to get from Buffalo to West Lafayette by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Lafayette Bus Stopbus bus FlixBus 2511 / ...
    12h 20m
    $85–130

  2. Fly to Purdue University Airport

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Purdue University Airport (LAF)plane plane BUF - LAF
    8h 13m
    $73–403

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train Cardinal
    15h 51m
    $357–693

  4. Drive  505.7 mi

    1. Drive from Buffalo to West Lafayettecar car 505.7 mi
    9h 5m
    $93–134

  5. Bus via Indianapolis

    1. Take the bus from Buffalo to Columbusbus bus
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus bus
    14h 45m
    $75–147

  6. Fly to Indianapolis, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 16m
    $115–592

  7. Fly to Chicago O'Hare International Airport, shuttle

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take a shuttle bus from O'Hare International Terminal 2 to West Lafayette, INshuttle bus
    8h 10m
    $203–363

  8. Fly to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 4m
    $229–427

Buffalo to West Lafayette by bus (Flixbus)

Calendar7Weekly Buses
Duration12h 20mAverage Duration
Ticket$85Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to West Lafayette.ExpandLaunch map view
  • Distance: 575.8 mi
  • Duration: 12h 20m

What companies run services between Buffalo, NY, USA and West Lafayette, IN, USA?

You can take a bus from Buffalo to Lafayette Bus Stop via Columbus in around 12h 20m. Alternatively, you can take a train from Buffalo to Lafayette Amtrak Station via Buffalo Depew Station and Chicago Union Station in around 15h 51m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There