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How to get fromBuffalo to Wilkesboroby plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

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There are 10 ways to get from Buffalo to Wilkesboro by plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the bus from Charlotte to Winston Salembus bus
    3. Take the bus from Winston-Salem to Wilkesborobus bus
    8h 50m
    $113–613

  2. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport, bus

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    2. Take the bus from Forsyth Hospital to Wilkesborobus bus
    9h 35m
    $87–380

  3. Bus

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Forsyth Hospital to Wilkesborobus bus
    18h 40m
    $94–206

  4. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Wilkesborobus bus
    24h 4m
    $532–835

  5. Drive  595.8 mi

    1. Drive from Buffalo to Wilkesborocar car 595.8 mi
    10h 48m
    $99–143

  6. Bus to Rochester, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    10h 4m
    $191–954

  7. Bus to Toronto Pearson International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane plane YYZ - CLT
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    12h 29m
    $137–670

  8. Bus to Rochester, fly to Concord, train, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    3. Take the train from Kannapolis to High Pointtrain train
    4. Take the bus from Forsyth Hospital to Wilkesborobus bus
    10h 32m
    $348–1,018

  9. Bus to Erie International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Eriebus bus
    2. Fly from Erie International Airport (ERI) to Charlotte Douglas International Airport (CLT)plane plane ERI - CLT
    3. Take the bus from Charlotte to Winston Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    12h 21m
    $130–639

  10. Bus via New York

    1. Take the bus from Buffalo to New York Midtownbus bus
    2. Take the bus from New York Midtown to Greensboro Bus Stopbus bus
    3. Take the bus from Greensboro to Winston-Salembus bus
    4. Take the bus from Winston-Salem to Wilkesborobus bus
    24h 45m
    $179–273

Buffalo to Wilkesboro by bus

Calendar7Weekly Buses
Duration24h 45mAverage Duration
Ticket$179Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Wilkesboro.ExpandLaunch map view
  • Distance: 709 mi
  • Duration: 8h 50m

What companies run services between Buffalo, NY, USA and Wilkesboro, NC, USA?

You can take a bus from Buffalo to Wilkesboro via Akron, Charleston, Charleston Bus Station, Winston Salem(Trans Center), Winston-Salem Transportation Center, and Forsyth Hospital in around 18h 40m.

Airlines
Train operators
Bus operators

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