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How to get fromBuffalo to Winston-Salemby plane, bus (Greyhound), car, bus, or bus (Flixbus, Greyhound)

Find Transport to Winston-Salem

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There are 6 ways to get from Buffalo to Winston-Salem by plane, bus (Greyhound), car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    6h 17m
    $86–415

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    15h 25m
    $83–191

  3. Drive  601.3 mi

    1. Drive from Buffalo to Winston-Salemcar car 601.3 mi
    10h 27m
    $110–159

  4. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 43m
    $119–679

  5. Bus to Rochester, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 57m
    $187–920

  6. Bus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus Greyhound US0140
    17h 2m
    $130–201

Buffalo to Winston-Salem by bus

Calendar7Weekly Buses
Duration15h 25mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Winston-Salem.ExpandLaunch map view
  • Distance: 511.6 mi
  • Duration: 6h 17m

What companies run services between Buffalo, NY, USA and Winston-Salem, NC, USA?

American Airlines, United Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Buffalo to Winston Salem(Trans Center) via Akron, Charleston, and Charleston Bus Station in around 15h 25m.

Airlines
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