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How to get fromBuffalo to Wiscassetby plane, bus, bus (Greyhound), train, car, taxi, train (Amtrak), or bus (Flixbus)

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There are 11 ways to get from Buffalo to Wiscasset by plane, bus, bus (Greyhound), train, car, taxi, train (Amtrak), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Boston Logan Airport, Amtrak Thruway

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from South Station to Wiscassetbus bus
    7h 41m
    $103–457

  2. Drive  552.5 mi

    cheapest
    1. Drive from Buffalo to Wiscassetcar car 552.5 mi
    11h 17m
    $101–146

  3. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston South Buses to Wiscassetbus bus Midcoast Maine to Bangor
    14h 20m
    $125–182

  4. Train, Amtrak Thruway (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from South Station to Wiscassetbus bus Boston
    16h 59m
    $312–614

  5. Fly Buffalo Niagara International Airport to Portland, Amtrak Thruway

    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    2. Take the bus from Portland, ME to Wiscassetbus bus
    8h 55m
    $102–510

  6. Fly Buffalo Niagara International Airport to Augusta State Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane plane BUF - AUG
    5h 53m
    $127–372

  7. Fly Buffalo Niagara International Airport to Rockland, taxi

    1. Fly from Buffalo Niagara International Airport (BUF) to Rockland (RKD)plane plane BUF - RKD
    2. Take the taxi from Rockland (RKD) to Wiscassettaxi taxi
    6h 34m
    $177–472

  8. Bus to Rochester, fly to Boston Logan Airport, Amtrak Thruway

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from South Station to Wiscassetbus bus
    8h 49m
    $151–658

  9. Train to Toronto Island Airport, fly to Boston Logan Airport, Amtrak Thruway

    1. Take the train from Buffalo to Toronto Union Stationtrain train
    2. Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)plane plane YTZ - BOS
    3. Take the bus from South Station to Wiscassetbus bus
    12h 32m
    $180–704

  10. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the train from Boston to Brunswick Amtrak Stationtrain train Downeaster
    17h 30m
    $400–762

  11. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Springfield Union Stationbus bus
    3. Take the bus from Springfield Union Station to Brunswick Stationbus bus
    18h 25m
    $110–222

Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS) flights

Calendar60Weekly Planes
Duration2h 34mAverage Duration
Ticket$62Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Wiscasset.ExpandLaunch map view
  • Distance: 562.7 mi
  • Duration: 7h 41m

What companies run services between Buffalo, NY, USA and Wiscasset, ME, USA?

You can take a bus from Buffalo to Wiscasset via Boston, Boston South Buses, and Wiscasset in around 14h 20m. Alternatively, JetBlue Airways, Cape Air, and four other airlines fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG) every 2 hours.

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