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How to get fromBuffalo to Woods Holeby plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

Find Transport to Woods Hole

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There are 7 ways to get from Buffalo to Woods Hole by plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Boston Logan Airport, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Boston to Woods Holebus bus
    6h 21m
    $77–420

  2. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston to Woods Holebus bus Bz 0531 / ...
    12h 50m
    $98–148

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston to Woods Holebus bus Bz 0531 / ...
    15h 33m
    $287–580

  4. Drive  510.1 mi

    1. Drive from Buffalo to Woods Holecar car 510.1 mi
    9h 1m
    $94–135

  5. Bus to Rochester, fly to Boston Logan Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from Boston to Woods Holebus bus
    7h 30m
    $125–621

  6. Fly Buffalo Niagara International Airport to Barnstable Municipal Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)plane plane BUF - HYA
    2. Take the bus from Hyannis Transportation Center to Steamship Authority Ferry Docks, Woods Holebus bus
    8h 14m
    $83–483

  7. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the bus from Boston to Woods Holebus bus
    15h 25m
    $95–154

Buffalo to Woods Hole by bus

Calendar7Weekly Buses
Duration12h 50mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Woods Hole.ExpandLaunch map view
  • Distance: 485.6 mi
  • Duration: 6h 21m

What companies run services between Buffalo, NY, USA and Woods Hole, MA, USA?

You can take a bus from Buffalo to Woods Hole via Boston in around 12h 50m.

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Train operators
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Need to know: Greyhound

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