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How to get fromBuffalo to Wythevilleby plane, bus, car, or bus (Greyhound, Flixbus)

Find Transport to Wytheville

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There are 10 ways to get from Buffalo to Wytheville by plane, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 28m
    $164–688

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston to Wythevillebus bus
    13h 14m
    $79–204

  3. Drive  518.7 mi

    1. Drive from Buffalo to Wythevillecar car 518.7 mi
    8h 56m
    $95–137

  4. Fly Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane BUF - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    9h 6m
    $84–409

  5. Fly Buffalo Niagara International Airport to Piedmont Triad International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Wythevillebus bus
    9h 30m
    $132–504

  6. Fly Buffalo Niagara International Airport to Washington Dulles International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane plane BUF - IAD
    2. Take the bus from Dulles International Airport to Wytheville Rural King Parking Lotbus bus
    9h 21m
    $97–447

  7. Bus to Rochester, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    8h 41m
    $232–929

  8. Bus to Rochester, fly to Concord, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    8h 1m
    $408–1,103

  9. Bus to Toronto Pearson International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane plane YYZ - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    11h 4m
    $173–635

  10. Bus via Washington

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Wytheville Rural King Parking Lotbus bus
    21h 30m
    $131–333

Buffalo to Wytheville by bus

Calendar7Weekly Buses
Duration21h 30mAverage Duration
Ticket$131Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Wytheville.ExpandLaunch map view
  • Distance: 712.8 mi
  • Duration: 7h 28m

What companies run services between Buffalo, NY, USA and Wytheville, VA, USA?

You can take a bus from Buffalo to Wytheville via Akron, Charleston, and Wytheville in around 13h 14m.

Airlines
Bus operators

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