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How to get fromBuffalo to Wythevilleby bus, car, plane, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Buffalo to Wytheville by bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Wythevillebus bus
    13h 14m
    $79–204

  2. Drive 518.7 mi

    1. Drive from Buffalo to Wythevillecar car 518.7 mi
    8h 56m
    $95–137

  3. Fly Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane BUF - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Route 460 Park and Ride to Rural King Shopping Centerbus bus
    8h 39m
    $98–528

  4. Bus via Charleston

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston, WV to Wythevillebus bus
    13h 14m

  5. Bus via Washington

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    3. Take the bus from DC Union Station to Rural King Shopping Centerbus bus
    21h 5m
    $126–358

  6. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 11m
    $192–869

  7. Fly Buffalo Niagara International Airport to Washington Dulles International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane plane BUF - IAD
    2. Take the bus from Dulles Airport to Rural King Shopping Centerbus bus
    8h 55m
    $97–493

  8. Bus to Rochester, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    8h 27m
    $220–886

  9. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    9h 29m
    $170–576

  10. Bus to Rochester, fly to Concord, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    3. Take the bus from Charlotte Bus Station to Max Meadowsbus bus
    7h 44m
    $416–1,110

Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA) flights

Calendar95Weekly Planes
Duration5h 29mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Wytheville.ExpandLaunch map view
  • Distance: 593.9 mi
  • Duration: 13h 14m

What companies run services between Buffalo, NY, USA and Wytheville, VA, USA?

You can take a bus from Buffalo, NY to Wytheville via Robert K Pfaff Transit Center - Akron, Charleston, WV, and Wytheville in around 13h 14m.

Airlines
Bus operators

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