There are 7 ways to get from Cafayate to Santiago by bus, plane, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Martín Miguel De Güemes International Airport, fly
best- Take the bus from Terminal de Ómnibus de Cafayate to Cerrillosbus
- Fly from Martín Miguel De Güemes International Airport (SLA) to Comodoro Arturo Merino Benítez International Airport (SCL)plane SLA - SCL
11h 7m$140–523Bus
cheapest- Take the bus from Cafayate to Terminal de Tucumánbus
- Take the bus from Terminal de Tucumán to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus
27h 8m$69–165Drive 1,317 km
- Drive from Cafayate to Santiagocar 1,317 km
18h 26m$163–235Bus, bus to Teniente General Benjamín Matienzo International Airport, fly
- Take the bus from Cafayate to Tafí del Vallebus
- Take the bus from Tafí del Valle to Terminal de Tucumánbus
- Fly from Teniente General Benjamín Matienzo International Airport (TUC) to Comodoro Arturo Merino Benítez International Airport (SCL)plane TUC - SCL
12h 49m$172–687Bus via Los Andes
- Take the bus from Cafayate to Tafí del Vallebus
- Take the bus from Tafí del Valle to Famaillábus
- Take the bus from Famaillá to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Los Andes - El Saucebus
- Take the bus from Espacio Urbano-Los Andes to Santiagobus
28h 10m$94–147Bus via Los Andes #2
- Take the bus from Cafayate to Tafí del Vallebus
- Take the bus from Tafí del Valle to Famaillábus
- Take the bus from Famaillá to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Los Andesbus
- Take the bus from Los Andes to Terminal Los Héroesbus
28h 13m$84–188Bus via Pajaritos Dirección San Pablo
- Take the bus from Cafayate to Terminal de Tucumánbus
- Take the bus from Terminal de Tucumán to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Terminal Alameda - Turbusbus
31h 11m$74–181
Martín Miguel De Güemes International Airport (SLA) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Comparing Your Travel Options
The cheapest way to get from Cafayate to Santiago is to bus which costs $65 - $170 and takes 27h 8m.
The fastest way to get from Cafayate to Santiago is to bus and fly which takes 11h 7m and costs $140 - $550.
No, there is no direct bus from Cafayate to Santiago. However, there are services departing from Cafayate and arriving at Terminal Sur de Santiago via Terminal de Tucumán and Terminal Mendoza. The journey, including transfers, takes approximately 27h 8m.
The distance between Cafayate and Santiago is 1286 km. The road distance is 1317 km.
The best way to get from Cafayate to Santiago without a car is to bus which takes 27h 8m and costs $65 - $170.
It takes approximately 11h 7m to get from Cafayate to Santiago, including transfers.
Cafayate to Santiago bus services, operated by Transporte Aconquija, depart from Cafayate station.
Cafayate to Santiago bus services, operated by Transporte Aconquija, arrive at Terminal de Tucumán station.
Yes, the driving distance between Cafayate to Santiago is 1317 km. It takes approximately 18h 26m to drive from Cafayate to Santiago.
There are 3388+ hotels available in Santiago.
What companies run services between Cafayate, Argentina and Santiago, Chile?
You can take a bus from Cafayate to Terminal Sur de Santiago via Terminal de Tucumán and Terminal Mendoza in around 27h 8m.
- Website
- jetsmart.com
Flights from Martín Miguel De Güemes International Airport to Comodoro Arturo Merino Benítez International Airport via Mendoza
- Ave. Duration
- 4h 20m
- When
- Monday
- Estimated price
- $130–450
Flights from Martín Miguel De Güemes International Airport to Comodoro Arturo Merino Benítez International Airport via Buenos Aires Jorge Newbery
- Ave. Duration
- 7h 24m
- When
- Sunday, Tuesday, and Thursday
- Estimated price
- $130–450
Flights from Teniente General Benjamín Matienzo International Airport to Comodoro Arturo Merino Benítez International Airport via Buenos Aires Jorge Newbery
- Ave. Duration
- 9h 24m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $370–700
- Phone
- 0810 222-5202
- [email protected]
- Website
- Flecha Bus
Bus from Terminal de Ómnibus de Cafayate to Cerrillos
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- $15–30
- Website
- Flecha Bus
- Cama
- $21–30
- Semi Cama
- $15–23
Bus from Terminal de Tucumán to Terminal Mendoza
- Ave. Duration
- 13h 35m
- Frequency
- 4 times a week
- Estimated price
- $45–89
- Website
- Flecha Bus
- Cama
- $60–85
- Semi Cama
- $45–70
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Train travel in France: A guide to SNCF, How to travel India's Golden Triangle, and Want to know more about Flixbus? - to help you get the most out of your next trip.




