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How to get fromCairo to St. Louisby taxi, plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Cairo to St. Louis by taxi, plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Tallahassee, fly to Lambert–St. Louis International Airport

    best
    1. Take the taxi from Cairo to Tallahassee (TLH)taxi taxi
    2. Fly from Tallahassee (TLH) to Lambert–St. Louis International Airport (STL)plane plane TLH - STL
    5h 26m
    $236–710

  2. Drive to Southwest Georgia Regional Airport, fly to Lambert–St. Louis International Airport

    cheapest
    1. Drive from Cairo to Southwest Georgia Regional Airport (ABY)car car
    2. Fly from Southwest Georgia Regional Airport (ABY) to Lambert–St. Louis International Airport (STL)plane plane ABY - STL
    6h 41m
    $108–567

  3. Bus via Carbondale

    1. Take the bus from Thomasville Travel Center to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    18h 32m
    $172–263

  4. Drive  753.4 mi

    1. Drive from Cairo to St. Louiscar car 753.4 mi
    13h 22m
    $134–193

  5. Drive to Valdosta, fly to Lambert–St. Louis International Airport

    1. Drive from Cairo to Valdosta (VLD)car car
    2. Fly from Valdosta (VLD) to Lambert–St. Louis International Airport (STL)plane plane VLD - STL
    5h 56m
    $114–568

  6. Drive to Destin–Fort Walton Beach Airport, fly to Lambert–St. Louis International Airport

    1. Drive from Cairo to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    5h 51m
    $122–596

  7. Drive to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport

    1. Drive from Cairo to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    6h 7m
    $120–455

  8. Bus

    1. Take the bus from Thomasville Travel Center to Atlanta Bus Stationbus bus Greyhound US0636s
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    18h 51m
    $177–290

Tallahassee (TLH) to Lambert–St. Louis International Airport (STL) flights

Calendar72Weekly Planes
Duration5h 31mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cairo to St. Louis.ExpandLaunch map view
  • Distance: 723.5 mi
  • Duration: 5h 26m

What companies run services between Cairo, GA, USA and St. Louis, MO, USA?

You can take a vehicle from Cairo to St. Louis via Thomasville Travel Center, Atlanta Bus Station, and Carbondale in around 18h 32m.

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