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How to get fromCalgary to Mayo Clinicby plane, bus, car, or train

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There are 4 ways to get from Calgary to Mayo Clinic by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Calgary International Airport (YYC) to Rochester (RST)plane plane YYC - RST
    8h 9m
    $95–481

  2. Bus, drive, train

    1. Take the bus from Calgary - Deerfoot Inn & Casino* to Lethbridge - U of Lbus bus
    2. Drive from Lethbridge - U of L to Port of Sweet Grasscar car
    3. Take the bus from Port of Sweet Grass to Shelby Transit Centerbus bus
    4. Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain train
    5. Take the bus from St. Paul to Rochesterbus bus
    29h 8m

  3. Drive  1,267.9 mi

    1. Drive from Calgary to Mayo Cliniccar car 1,267.9 mi
    22h 23m
    $291–420

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Calgary International Airport (YYC) to Minneapolis–Saint Paul International Airport (MSP)plane plane YYC - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 40m
    $277–842

Calgary International Airport (YYC) to Rochester (RST) flights

Calendar55Weekly Planes
Duration7h 55mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Calgary to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,134.8 mi
  • Duration: 8h 9m

What companies run services between Calgary, AB, Canada and Mayo Clinic, MN, USA?

WestJet, Delta, and American Airlines fly from Calgary International Airport (YYC) to Rochester (RST) every 4 hours.

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