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How to get fromCalgary to Mayo Clinicby plane, bus, car, or train

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There are 4 ways to get from Calgary to Mayo Clinic by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Calgary International Airport (YYC) to Rochester (RST)plane plane YYC - RST
    10h 29m
    $91–474

  2. Bus, drive, train

    1. Take the bus from Calgary Downtown Ticket Office 606 5 Ave SW to Lethbridge - University Transit Loopbus bus
    2. Drive from Lethbridge - University Transit Loop to Port of Sweet Grasscar car
    3. Take the bus from Port of Sweet Grass to Shelby Transit Centerbus bus
    4. Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain train
    5. Take the bus from St. Paul to Rochesterbus bus
    30h 11m

  3. Drive  1,267.9 mi

    1. Drive from Calgary to Mayo Cliniccar car 1,267.9 mi
    22h 23m
    $291–420

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Calgary International Airport (YYC) to Minneapolis–Saint Paul International Airport (MSP)plane plane YYC - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 3m
    $180–874

Calgary International Airport (YYC) to Rochester (RST) flights

Calendar44Weekly Planes
Duration8h 33mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Calgary to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,134.8 mi
  • Duration: 10h 29m

What companies run services between Calgary, AB, Canada and Mayo Clinic, MN, USA?

Delta, American Airlines, and WestJet fly from Calgary International Airport (YYC) to Rochester (RST) every 4 hours.

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