There are 7 ways to get from Cali to Antioquia by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Medellin Jose Marie Cordova
best- Fly from Cali (CLO) to Medellin Jose Marie Cordova (MDE)plane CLO - MDE
2h 10m$100–234Drive 422.4 km
cheapest- Drive from Cali to Medellíncar 422.4 km
7h 13m$22–32Bus
- Take the bus from Terminal de Transporte Cali to Terminal del Surbus
8h 24m$26–41Fly to Enrique Olaya Herrera Airport
- Fly from Cali (CLO) to Enrique Olaya Herrera Airport (EOH)plane CLO - EOH
2h 9m$236–2,230Bus via Buga
- Take the bus from Terminal de Transporte Cali to Bugabus
- Take the bus from Buga to Terminal del Nortebus Cali
9h 7m$34–46Bus via Terminal de Transporte Cali
- Take the bus from Terminal de Transporte Cali to Terminal del Surbus
9h 9m$33–46Bus via Manizales
- Take the bus from Terminal de Transporte Cali to Terminal de Transportes de Manizalesbus
- Take the bus from Terminal de Transportes de Manizales to Terminal del Nortebus
10h 7m$38–48
Cali (CLO) to Medellin Jose Marie Cordova (MDE) flights
Questions & Answers
The cheapest way to get from Cali to Antioquia is to drive which costs $22 - $35 and takes 7h 13m.
The fastest way to get from Cali to Antioquia is to fly which takes 2h 9m and costs $230 - $2,300.
No, there is no direct bus from Cali to Antioquia. However, there are services departing from Terminal de Transporte Cali and arriving at Exposiciones via Terminal del Sur. The journey, including transfers, takes approximately 8h 24m.
The distance between Cali and Antioquia is 357 km. The road distance is 422.4 km.
The best way to get from Cali to Antioquia without a car is to bus which takes 8h 24m and costs $26 - $45.
It takes approximately 2h 10m to get from Cali to Antioquia, including transfers.
Cali to Antioquia bus services, operated by Expreso Trejos, depart from Terminal de Transporte Cali station.
The best way to get from Cali to Antioquia is to fly which takes 2h 10m and costs $95 - $240. Alternatively, you can bus, which costs $26 - $45 and takes 8h 24m.
Cali to Antioquia bus services, operated by Expreso Trejos, arrive at Terminal del Sur station.
Yes, the driving distance between Cali to Antioquia is 422 km. It takes approximately 7h 13m to drive from Cali to Antioquia.
What companies run services between Cali, Colombia and Antioquia, Colombia?
JetSMART, LATAM Chile, and Avianca - Aerovías del Continente Americano S.A. fly from Cali (CLO) to Medellin Jose Marie Cordova (MDE) every 3 hours. Alternatively, Expreso Trejos operates a bus from Terminal de Transporte Cali to Terminal del Sur 4 times a day. Tickets cost $32 and the journey takes 7h 45m. Bolivariano also services this route every 3 hours.
- Website
- jetsmart.com
Flights from Cali to Medellin Jose Marie Cordova
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $40–90
- Website
- avianca.com
Flights from Cali to Medellin Jose Marie Cordova
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $50–140
Flights from Cali to Enrique Olaya Herrera Airport via Bogota
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- $200–850
- Website
- easyfly.com.co
Flights from Cali to Enrique Olaya Herrera Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $240–750
- Website
- latam.com
Flights from Cali to Medellin Jose Marie Cordova
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $50–100
- Phone
- +57 313 2499101
- [email protected]
- Website
- trejos.co
Bus from Terminal de Transporte Cali to Terminal del Sur
- Ave. Duration
- 7h 45m
- Frequency
- 4 times a day
- Estimated price
- $32
- Schedules at
- pinbus.com
- Book at
- pinbus.com
Bus from Terminal de Transporte Cali to Terminal de Transportes de Manizales
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $19
- Schedules at
- pinbus.com
- Book at
- pinbus.com
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal de Transporte Cali to Terminal del Sur
- Ave. Duration
- 10h
- Frequency
- Every 3 hours
- Estimated price
- $25–40
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 318 760 6799
- [email protected]
- Website
- cootrancise.com
Bus from Terminal de Transporte Cali to Buga
- Ave. Duration
- 1h
- Frequency
- Every 15 minutes
- Estimated price
- $5
- Schedules at
- cootrancise.com
- Phone
- +57 311 273 0419
- [email protected]
- Website
- expresopalmira.com.co
Bus from Buga to Terminal del Norte
- Ave. Duration
- 7h
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Schedules at
- expresopalmira.com.co
- Book at
- expresopalmira.com.co
- Phone
- 01 8000 42 37 87
- [email protected]
- Website
- empresaarauca.com
Bus from Terminal de Transporte Cali to Terminal del Sur
- Ave. Duration
- 8h 30m
- Frequency
- Every 3 hours
- Estimated price
- $30–45
- Schedules at
- empresaarauca.com
- Basico
- $30–45
- Phone
- +57 310 612 5292
- [email protected]
- Website
- flotaospina.com
Bus from Terminal de Transporte Cali to Terminal de Transportes de Manizales
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $21
- Schedules at
- flotaospina.com
- Phone
- +57 314 880 8888
- [email protected]
- Website
- taxlaferia.co
Bus from Terminal de Transportes de Manizales to Terminal del Norte
- Ave. Duration
- 4h
- Frequency
- Every 3 hours
- Estimated price
- $19–27
- Schedules at
- taxlaferia.co
- Book at
- taxlaferia.teletiquete.com
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Flying into Beijing?, Italy Travel Guides, and What are the different types of Renfe trains in Spain? - to help you get the most out of your next trip.
More Questions & Answers
There are 2873+ hotels available in Antioquia.



















