There are 6 ways to get from Cali to Guayaquil by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Cali
best- Fly from Cali (CLO) to José Joaquín De Olmedo International Airport (GYE)plane CLO - GYE
6h 25m$222–504Bus
cheapest- Take the bus from Terminal de Transporte Cali to Ipialesbus
- Take the bus from Tulcán to Terminal Terrestre de Guayaquilbus Guayaquil
26h 14m$45–68Bus, drive
- Take the bus from Terminal de Transporte Cali to Ipialesbus
- Drive from Ipiales to San Gabrielcar
- Take the bus from San Gabriel to Quito Terminal Carcelénbus
- Take the bus from Quito Terminal Carcelén to Guayaquilbus
23h 17m$53–80Drive 1,086.6 km
- Drive from Cali to Guayaquilcar 1,086.6 km
18h 58m$130–187Bus to Popayan Airport, fly
- Take the bus from Terminal de Transporte Cali to Terminal Popayánbus
- Fly from Popayan Airport (PPN) to José Joaquín De Olmedo International Airport (GYE)plane PPN - GYE
10h 5m$281–1,119Bus via Ibarra
- Take the bus from Terminal de Transporte Cali to Terminal de Pastobus
- Take the bus from Terminal de Pasto to Terminales de Transportes de Ipialesbus
- Take the bus from Tulcán to Ibarrabus
- Take the bus from Ibarra to Terminal Terrestre de Guayaquilbus
26h 24m$50–69
Cali (CLO) to José Joaquín De Olmedo International Airport (GYE) flights
Comparing Your Travel Options
The cheapest way to get from Cali to Guayaquil is to bus which costs $40 - $70 and takes 26h 14m.
The fastest way to get from Cali to Guayaquil is to fly which takes 6h 25m and costs $220 - $550.
No, there is no direct bus from Cali to Guayaquil. However, there are services departing from Terminal de Transporte Cali and arriving at Terminal Terrestre de Guayaquil via Tulcán. The journey, including transfers, takes approximately 26h 14m.
The distance between Cali and Guayaquil is 762 km. The road distance is 1086.6 km.
It takes approximately 6h 25m to get from Cali to Guayaquil, including transfers.
Cali to Guayaquil bus services, operated by Bolivariano, depart from Terminal de Transporte Cali station.
The best way to get from Cali to Guayaquil is to fly which takes 6h 25m and costs $220 - $550. Alternatively, you can bus, which costs $40 - $70 and takes 26h 14m.
Cali to Guayaquil bus services, operated by Bolivariano, arrive at Ipiales station.
Yes, the driving distance between Cali to Guayaquil is 1087 km. It takes approximately 18h 58m to drive from Cali to Guayaquil.
There are 419+ hotels available in Guayaquil.
What companies run services between Cali, Colombia and Guayaquil, Ecuador?
Avianca - Aerovías del Continente Americano S.A. and Copa Airlines fly from Cali (CLO) to José Joaquín De Olmedo International Airport (GYE) every 3 hours. Alternatively, you can take a bus from Terminal de Transporte Cali to Terminal Terrestre de Guayaquil via Ipiales and Tulcán in around 26h 14m.
- Website
- avianca.com
Flights from Cali to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $270–750
Flights from Cali to José Joaquín De Olmedo International Airport via Medellin Jose Marie Cordova
- Ave. Duration
- 8h 10m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $270–750
Flights from Popayan Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $270–1,100
Flights from Popayan Airport to José Joaquín De Olmedo International Airport via Bogota, Medellin Jose Marie Cordova
- Ave. Duration
- 7h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $290–1,200
- Website
- copaair.com
Flights from Cali to José Joaquín De Olmedo International Airport via Panama City
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $90–440
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 12h
- Frequency
- Every 3 hours
- Estimated price
- $24–45
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 12h
- Frequency
- Every 3 hours
- Estimated price
- $24–45
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminal de Pasto to Terminales de Transportes de Ipiales
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $6–9
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 314 8300867
- [email protected]
- Website
- cootranar.com
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 10h
- Frequency
- 3 times a day
- Estimated price
- $33
- Schedules at
- cootranar.com
- Book at
- redbus.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 10h
- Frequency
- 3 times a day
- Estimated price
- $33
- Schedules at
- cootranar.com
- Book at
- redbus.co
- Phone
- +593 6 2290185
- Website
- ecuador-turistico.com
Bus from San Gabriel to Quito Terminal Carcelén
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- $6
- Schedules at
- facebook.com
- Phone
- +593 96 297 2979
- [email protected]
- Website
- Trans Esmeraldas S.A.
Bus from Quito Terminal Carcelén to Guayaquil
- Ave. Duration
- 5h 34m
- Frequency
- Twice daily
- Estimated price
- $16–22
- Schedules at
- Trans Esmeraldas S.A.
- Phone
- 01-8000-910293
- [email protected]
- Website
- coomotor.com.co
Bus from Terminal de Transporte Cali to Terminal Popayán
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $11–19
- Schedules at
- coomotor.com.co
- Phone
- +593 95 885 1254
- [email protected]
- Website
- microsancristobal.com
Bus from Tulcán to Terminal Terrestre de Guayaquil
- Ave. Duration
- 13h
- Frequency
- Every 4 hours
- Estimated price
- $19–22
- Book at
- busplace.com
- Phone
- +57 317 441 0917
- [email protected]
- Website
- transipialesvirtual.com
Bus from Terminal de Transporte Cali to Terminal de Pasto
- Ave. Duration
- 10h
- Frequency
- Hourly
- Estimated price
- $24–35
- Schedules at
- transipialesvirtual.com
- Book at
- transipialesvirtual.com
- Basico
- $24–35
- Phone
- +57 312 831 0115
- [email protected]
- Website
- flotaguaitara.co
Bus from Terminal de Transporte Cali to Terminal de Pasto
- Ave. Duration
- 8h
- Frequency
- Twice daily
- Estimated price
- $28
- Schedules at
- terminalcali.com
- Phone
- +593 062980728
- [email protected]
- Website
- Cooperativa Tax Gacela
Bus from Tulcán to Ibarra
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- $3–7
- Schedules at
- Cooperativa Tax Gacela
Bus from Tulcán to Ibarra
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Website
- Compañía Expreso Turismo del Norte
- Phone
- +593 98 875 2804
- [email protected]
- Website
- Cooperativa de Transportes Aerotaxi
Bus from Ibarra to Terminal Terrestre de Guayaquil
- Ave. Duration
- 9h 10m
- Frequency
- Hourly
- Estimated price
- $15–16
- Website
- Cooperativa de Transportes Aerotaxi
- Website
- Cooperativa de Transportes Aerotaxi
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