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How to get fromCali to Santa Cruzby plane, bus, or car

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There are 4 ways to get from Cali to Santa Cruz by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Cali (CLO) to Viru Viru International Airport (VVI)plane plane CLO - VVI
    7h 4m
    $355–730

  2. Drive 4,719.5 km

    cheapest
    1. Drive from Cali to Santa Cruz de la Sierracar car 4,719.5 km
    2d 21h
    $247–356

  3. Bus via Lima

    1. Take the bus from Terminal de Transporte Cali to Ipialesbus bus
    2. Take the bus from Rumichaca to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Lima - Terminal Arriola to La Pazbus bus
    4. Take the bus from La Paz to Santa Cruzbus bus
    3d 19h
    $258–824

  4. Bus

    1. Take the bus from Terminal de Transporte Cali to Ipialesbus bus
    2. Take the bus from Rumichaca to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Oltursa Lima Terminal to La Pazbus bus
    4. Take the bus from La Paz to Santa Cruzbus bus
    3d 19h
    $289–417

Cali (CLO) to Viru Viru International Airport (VVI) flights

Calendar33Weekly Planes
Duration8h 43mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

Map of how to get from Cali to Santa Cruz.ExpandLaunch map view
  • Distance: 2,810.1 km
  • Duration: 7h 4m

What companies run services between Cali, Colombia and Santa Cruz, Bolivia?

Avianca - Aerovías del Continente Americano S.A., Copa Airlines, and JetSMART fly from Cali (CLO) to Viru Viru International Airport (VVI) 5 times a day. Alternatively, you can take a bus from Terminal de Transporte Cali to Santa Cruz de la Sierra via Ipiales, Terminal Ipiales, Rumichaca, Gran Terminal Terrestre Plaza Norte, Lima Nicolas Arriola, Lima - Terminal Arriola, La Paz, and Santa Cruz in around 3d 19h.

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