There are 4 ways to get from Cali to Santa Cruz de la Sierra by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Cali (CLO) to Viru Viru International Airport (VVI)plane CLO - VVI
7h 4m$236–880Bus via Lima
- Take the bus from Terminal de Transporte Cali to Ipialesbus
- Take the bus from Rumichaca to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Lima - Terminal Arriola to La Pazbus
- Take the bus from La Paz to Santa Cruzbus
3d 18h$256–821Drive 4,719.5 km
- Drive from Cali to Santa Cruz de la Sierracar 4,719.5 km
2d 21h$247–356Bus
- Take the bus from Terminal de Transporte Cali to Ipialesbus
- Take the bus from Rumichaca to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Oltursa Lima Terminal to La Pazbus
- Take the bus from La Paz to Santa Cruzbus
3d 19h$288–414
Cali (CLO) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Cali to Santa Cruz de la Sierra is to drive which costs $240 - $360 and takes 2 days 21h.
The fastest way to get from Cali to Santa Cruz de la Sierra is to fly which takes 7h 4m and costs $230 - $900.
No, there is no direct bus from Cali to Santa Cruz de la Sierra. However, there are services departing from Terminal de Transporte Cali and arriving at Santa Cruz via Terminal Ipiales, Rumichaca, Gran Terminal Terrestre Plaza Norte, Lima - Terminal Arriola and La Paz. The journey, including transfers, takes approximately 3 days 18h.
The distance between Cali and Santa Cruz de la Sierra is 2810 km. The road distance is 4719.5 km.
The best way to get from Cali to Santa Cruz de la Sierra without a car is to bus via Lima which takes 3 days 18h and costs $250 - $850.
It takes approximately 7h 4m to get from Cali to Santa Cruz de la Sierra, including transfers.
Cali to Santa Cruz de la Sierra bus services, operated by Bolivariano, depart from Terminal de Transporte Cali station.
The best way to get from Cali to Santa Cruz de la Sierra is to fly which takes 7h 4m and costs $230 - $900. Alternatively, you can bus via Lima, which costs $250 - $850 and takes 3 days 18h.
Cali to Santa Cruz de la Sierra bus services, operated by Bolivariano, arrive at Ipiales station.
Santa Cruz de la Sierra is 1h ahead of Cali. It is currently 10:35 AM in Cali and 11:35 AM in Santa Cruz de la Sierra.
What companies run services between Cali, Colombia and Santa Cruz de la Sierra, Bolivia?
Avianca - Aerovías del Continente Americano S.A., Copa Airlines, and JetSMART fly from Cali (CLO) to Viru Viru International Airport (VVI) 4 times a day. Alternatively, you can take a bus from Terminal de Transporte Cali to Santa Cruz via Ipiales, Terminal Ipiales, Rumichaca, Gran Terminal Terrestre Plaza Norte, Lima Nicolas Arriola, Lima - Terminal Arriola, and La Paz in around 3d 18h.
- Website
- avianca.com
Flights from Cali to Viru Viru International Airport via Bogota
- Ave. Duration
- 6h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,100
Flights from Cali to Viru Viru International Airport via Pasto, Bogota
- Ave. Duration
- 10h 35m
- When
- Every day
- Estimated price
- $330–1,200
Flights from Cali to Viru Viru International Airport via Medellin Jose Marie Cordova, Bogota
- Ave. Duration
- 10h 45m
- When
- Every day
- Estimated price
- $320–1,200
- Website
- copaair.com
Flights from Cali to Viru Viru International Airport via Panama City
- Ave. Duration
- 8h 50m
- When
- Every day
- Estimated price
- $210–850
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 12h
- Frequency
- Every 3 hours
- Estimated price
- $17–45
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 12h
- Frequency
- Every 3 hours
- Estimated price
- $17–45
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 314 8300867
- [email protected]
- Website
- cootranar.com
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 10h
- Frequency
- 3 times a day
- Estimated price
- $34
- Schedules at
- cootranar.com
- Book at
- redbus.co
Bus from Terminal de Transporte Cali to Ipiales
- Ave. Duration
- 10h
- Frequency
- 3 times a day
- Estimated price
- $34
- Schedules at
- cootranar.com
- Book at
- redbus.co
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- facebook.com
Bus from Rumichaca to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 26h 52m
- Frequency
- Once daily
- Estimated price
- $130–160
- Website
- https://www.facebook.com/lineasdelosandesve/
Bus from Rumichaca to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 26h 52m
- Frequency
- Once daily
- Estimated price
- $130–160
- Website
- https://www.facebook.com/lineasdelosandesve/
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Lima - Terminal Arriola to La Paz
- Ave. Duration
- 29h
- Frequency
- Once daily
- Estimated price
- $100–550
- Book at
- https://www.ticketsbolivia.com/company/nc_internacional.php
- Phone
- +591-72233555
- [email protected]
- Website
- transcopacabanasa.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- transcopacabanasa.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- transcopacabanasa.com
- Phone
- +591 7297 1111
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- facebook.com
- Phone
- +591 69414917
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- facebook.com
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- facebook.com
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
- Phone
- +591 69416892
- [email protected]
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- facebook.com
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
- Phone
- +591 2245 8945
- [email protected]
- Website
- vicuna-travel.com
Bus from Oltursa Lima Terminal to La Paz
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $103
- Schedules at
- ticketsbolivia.com.bo
- Book at
- ticketsbolivia.com.bo
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including The beginner’s guide to the 2018 World Nomad Games, Need to know: Jadrolinija, and How do I get from Sydney to Melbourne - to help you get the most out of your next trip.
More Questions & Answers
Yes, the driving distance between Cali to Santa Cruz de la Sierra is 4720 km. It takes approximately 2 days 21h to drive from Cali to Santa Cruz de la Sierra.
There are 753+ hotels available in Santa Cruz de la Sierra.





















