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How to get fromCalifornia to Florenceby plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

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There are 6 ways to get from California to Florence by plane, train, bus, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Diego International Airport to Florence Regional Airport

    best
    1. Fly from San Diego International Airport (SAN) to Florence Regional Airport (FLO)plane plane SAN - FLO
    10h 29m
    $132–508

  2. Train, bus

    1. Take the train from Los Angeles to Houstontrain train
    2. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 10h
    $1,080–1,630

  3. Bus

    1. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    2d 12h
    $470–724

  4. Drive  2,446.7 mi

    1. Drive from Los Angeles to Florencecar car 2,446.7 mi
    39h 1m
    $447–645

  5. Fly John Wayne Airport Orange County to Charlotte Douglas International Airport, bus

    1. Fly from John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT)plane plane SNA - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    10h 22m
    $277–1,002

  6. Train (Amtrak)

    1. Take the train from Los Angeles to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    3d 1h
    $1,866–2,983

California to Florence by bus

Calendar7Weekly Buses
Duration2d 12hAverage Duration
Ticket$470Cheapest Price
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Comparing Your Travel Options

Map of how to get from California to Florence.ExpandLaunch map view
  • Distance: 2,155.8 mi
  • Duration: 10h 29m

What companies run services between California, USA and Florence, SC, USA?

American Airlines and Southwest Airlines fly from San Diego International Airport (SAN) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Los Angeles Union Station to Florence Bus Station via St Louis Bus Station and Atlanta Bus Station in around 2d 12h.

Airlines
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Want to know more about travelling around United States

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