What is the cheapest way to get from Cancún to Cayo Guillermo?

The cheapest way to get from Cancún to Cayo Guillermo is to fly and bus and drive which costs $120 - $480 and takes 28h 6m.

What is the fastest way to get from Cancún to Cayo Guillermo?

The fastest way to get from Cancún to Cayo Guillermo is to fly and train and taxi which takes 10h 47m and costs $170 - $550.

How far is it from Cancún to Cayo Guillermo?

The distance between Cancún and Cayo Guillermo is 1123 km.

How long does it take to get from Cancún to Cayo Guillermo?

It takes approximately 28h 6m to get from Cancún to Cayo Guillermo, including transfers.

What is the time difference between Cancún and Cayo Guillermo?

Cayo Guillermo is 1h ahead of Cancún. It is currently 11:59 AM in Cancún and 12:59 PM in Cayo Guillermo.

Cancún to Cayo Guillermo - 3 ways to travel via train, plane, bus, car

How to get fromCancún to Cayo Guillermo

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There are 3 ways to get from Cancún to Cayo Guillermo by plane, bus, car, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Abel Santamaría Airport, bus, drive
best
1. Fly from Cancún International Airport (CUN) to Abel Santamaría Airport (SNU)plane CUN - SNU
2. Take the bus from Santa Clara to Cayo Santa Maríabus
3. Drive from Cayo Santa María to Cayo Guillermocar
28h 6m
$126–475
Fly to Ignacio Agramonte International Airport, train, taxi
1. Fly from Cancún International Airport (CUN) to Ignacio Agramonte International Airport (CMW)plane CUN - CMW
2. Take the train from Camagüey to Moróntrain
3. Take the taxi from Morón to Cayo Guillermotaxi
10h 47m
$170–522
Fly to José Martí International Airport, bus, drive
1. Fly from Cancún International Airport (CUN) to José Martí International Airport (HAV)plane CUN - HAV
2. Take the bus from Havana Airport to Matanzasbus
3. Take the bus from Matanzas to Santa Clarabus
4. Take the bus from Santa Clara to Cayo Santa Maríabus
5. Drive from Cayo Santa María to Cayo Guillermocar
16h 55m
$221–1,040

Cancún International Airport (CUN) to Abel Santamaría Airport (SNU) flights

25Weekly Planes

20h 50mAverage Duration

$77Cheapest Price

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Questions & Answers

Map of how to get from Cancún to Cayo Guillermo.

Launch map view

Distance: 1,123.3 km
Duration: 28h 6m

What companies run services between Cancún, Mexico and Cayo Guillermo, Cuba?

There is no direct connection from Cancún to Cayo Guillermo. However, you can take the bus to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Abel Santamaría Airport (SNU), take the taxi to Santa Clara, take the bus to Cayo Santa María, then drive to Cayo Guillermo. Alternatively, you can take the bus to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Ignacio Agramonte International Airport (CMW), walk to Albaiza, take the bus to Camaguey, walk to Camagüey, take the train to Morón, then take the taxi to Cayo Guillermo.

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