There are 8 ways to get from Cancún to Panama City Beach by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Northwest Florida Beaches International Airport
best- Fly from Cancún International Airport (CUN) to Northwest Florida Beaches International Airport (ECP)plane CUN - ECP
7h 43m$152–532Fly to Destin–Fort Walton Beach Airport, drive
cheapest- Fly from Cancún International Airport (CUN) to Destin–Fort Walton Beach Airport (VPS)plane CUN - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar
8h 33m$107–473Bus
- Take the bus from Terminal de Autobuses ADO Cancún to Villahermosabus
- Take the bus from Villahermosa to Reynosabus
- Take the bus from McAllen Central Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus
2d 13h$380–698Drive 2,330.6 mi
- Drive from Cancún to Panama City Beachcar 2,330.6 mi
45h 17m$426–615Fly to Dothan Regional Airport, drive
- Fly from Cancún International Airport (CUN) to Dothan Regional Airport (DHN)plane CUN - DHN
- Drive from Dothan Regional Airport (DHN) to Panama City Beachcar
9h 41m$114–483Fly to Pensacola International Airport, bus
- Fly from Cancún International Airport (CUN) to Pensacola International Airport (PNS)plane CUN - PNS
- Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus
10h 24m$111–448Fly to Tallahassee, bus
- Fly from Cancún International Airport (CUN) to Tallahassee (TLH)plane CUN - TLH
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus
10h 28m$159–627Bus via Puebla
- Take the bus from Terminal de Autobuses ADO Cancún to Puebla Capubus
- Take the bus from Puebla CAPU to San Luis Potosíbus
- Take the bus from San Luis Potosí to McAllen Central Stationbus
- Take the bus from McAllen Central Station to Houston - Harrisburg Blvdbus
- Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus
2d 21h$446–747
Cancún International Airport (CUN) to Northwest Florida Beaches International Airport (ECP) flights
Questions & Answers
The cheapest way to get from Cancún to Panama City Beach is to fly and bus which costs $110 - $450 and takes 10h 24m.
The fastest way to get from Cancún to Panama City Beach is to fly which takes 7h 43m and costs $150 - $550.
No, there is no direct bus from Cancún to Panama City Beach station. However, there are services departing from Terminal de Autobuses ADO Cancún and arriving at Panama City Beach Bus Station via Villahermosa, Reynosa, McAllen Central Station and Houston Bus Station. The journey, including transfers, takes approximately 2 days 13h.
The distance between Cancún and Panama City Beach is 675 miles. The road distance is 2344.2 miles.
The best way to get from Cancún to Panama City Beach without a car is to bus which takes 2 days 13h and costs $380 - $700.
It takes approximately 7h 43m to get from Cancún to Panama City Beach, including transfers.
Cancún to Panama City Beach bus services, operated by ADO, depart from Terminal de Autobuses ADO Cancún station.
The best way to get from Cancún to Panama City Beach is to fly which takes 7h 43m and costs $150 - $550. Alternatively, you can bus, which costs $380 - $700 and takes 2 days 13h.
Cancún to Panama City Beach bus services, operated by ADO, arrive at Villahermosa station.
Yes, the driving distance between Cancún to Panama City Beach is 2344 miles. It takes approximately 45h 17m to drive from Cancún to Panama City Beach.
What companies run services between Cancún, Mexico and Panama City Beach, FL, USA?
Southwest Airlines, Delta, and two other airlines fly from Cancún International Airport (CUN) to Northwest Florida Beaches International Airport (ECP) 5 times a day. Alternatively, you can take a bus from Terminal de Autobuses ADO Cancún to Panama City Beach via Villahermosa, Reynosa, McAllen Central Station, Houston Bus Station, and Panama City Beach Bus Station in around 2d 13h.
- Website
- delta.com
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $100–460
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $100–470
Flights from Cancún International Airport to Dothan Regional Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $95–450
Flights from Cancún International Airport to Dothan Regional Airport via Miami, Atlanta
- Ave. Duration
- 8h 51m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–500
Flights from Cancún International Airport to Dothan Regional Airport via Nashville, Atlanta
- Ave. Duration
- 9h 36m
- When
- Saturday
- Estimated price
- $120–550
Flights from Cancún International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $90–420
Flights from Cancún International Airport to Tallahassee via Atlanta
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $120–600
- Website
- aeromexico.com
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $100–460
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $100–470
Flights from Cancún International Airport to Dothan Regional Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $95–450
Flights from Cancún International Airport to Dothan Regional Airport via Miami, Atlanta
- Ave. Duration
- 8h 51m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–500
Flights from Cancún International Airport to Dothan Regional Airport via Nashville, Atlanta
- Ave. Duration
- 9h 36m
- When
- Saturday
- Estimated price
- $120–550
Flights from Cancún International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $90–420
Flights from Cancún International Airport to Tallahassee via Atlanta
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Houston Hobby Apt
- Ave. Duration
- 6h
- When
- Monday to Wednesday
- Estimated price
- $110–550
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via St. Louis
- Ave. Duration
- 6h 35m
- When
- Saturday
- Estimated price
- $150–650
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 6h 55m
- When
- Sunday
- Estimated price
- $120–550
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Houston Hobby Apt
- Ave. Duration
- 5h 10m
- When
- Sunday
- Estimated price
- $110–500
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via St. Louis
- Ave. Duration
- 5h 50m
- When
- Sunday
- Estimated price
- $150–650
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 7h 50m
- When
- Sunday
- Estimated price
- $120–550
Flights from Cancún International Airport to Pensacola International Airport via Houston Hobby Apt
- Ave. Duration
- 6h 10m
- When
- Saturday to Friday
- Estimated price
- $100–440
Flights from Cancún International Airport to Pensacola International Airport via Nashville
- Ave. Duration
- 7h
- When
- Sunday
- Estimated price
- $100–470
- Website
- aa.com
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 7h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–550
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Miami
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $95–450
Flights from Cancún International Airport to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $120–550
Flights from Cancún International Airport to Pensacola International Airport via Miami
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $85–400
Flights from Cancún International Airport to Tallahassee via Miami
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $110–550
Flights from Cancún International Airport to Tallahassee via Charlotte
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $150–700
Flights from Cancún International Airport to Tallahassee via Dallas/Ft.Worth
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $180–800
- Website
- united.com
Flights from Cancún International Airport to Northwest Florida Beaches International Airport via Houston
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $110–550
Flights from Cancún International Airport to Pensacola International Airport via Houston
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $100–450
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 25m
- Frequency
- Every 30 minutes
- Estimated price
- $90–150
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Villahermosa to Reynosa
- Ave. Duration
- 22h 50m
- Frequency
- Twice daily
- Estimated price
- $160–230
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Puebla Capu
- Ave. Duration
- 25h 45m
- Frequency
- Every 4 hours
- Estimated price
- $120–250
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 40m
- Frequency
- Every 4 hours
- Estimated price
- $90–170
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Villahermosa
- Ave. Duration
- 14h 55m
- Frequency
- 3 times a day
- Estimated price
- $60–95
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Houston Bus Station to Panama City Beach Bus Station
- Ave. Duration
- 12h 50m
- Frequency
- Twice daily
- Estimated price
- $95–180
- Website
- Greyhound
Bus from Pensacola Airport to Panama City Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $15–29
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Houston Bus Station to Panama City Beach Bus Station
- Ave. Duration
- 12h 50m
- Frequency
- Twice daily
- Estimated price
- $95–180
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $55–100
- Schedules at
- Flixbus USA
- Phone
- +52 800 800 0386
- [email protected]
- Website
- ETN Turistar
Bus from Puebla CAPU to San Luis Potosí
- Ave. Duration
- 7h 16m
- Frequency
- 5 times a day
- Estimated price
- $70–100
- Website
- ETN Turistar
- Phone
- +1 800 923 1799
- [email protected]
- Website
- Omnibus Express (OMEX VIP)
Bus from San Luis Potosí to McAllen Central Station
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $70–110
- Schedules at
- Omnibus Express (OMEX VIP)
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from McAllen Central Station to Houston - Harrisburg Blvd
- Ave. Duration
- 7h 34m
- Frequency
- Once daily
- Estimated price
- $75–95
- Schedules at
- Omnibus Express
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