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How to get fromCancún to Sanibelby plane, bus, car, taxi, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Cancún to Sanibel by plane, bus, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from Cancún International Airport (CUN) to Ft. Myers (RSW)plane plane CUN - RSW
    7h 42m
    $157–532

  2. Bus

    1. Take the bus from Terminal de Autobuses ADO Cancún to Villahermosabus bus
    2. Take the bus from Villahermosa to Reynosabus bus
    3. Take the bus from McAllen Central Station to Houston - Harrisburg Blvdbus bus
    4. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 22h
    $516–790

  3. Drive 2,802 mi

    1. Drive from Cancún to Sanibelcar car 2,802 mi
    2d 5h
    $512–739

  4. Fly to Miami International Airport, bus, taxi

    1. Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane plane CUN - MIA
    2. Take the bus from Miami Airport to Fort Myers 7-11bus bus
    3. Take the taxi from Fort Myers 7-11 to Sanibeltaxi taxi
    8h 17m
    $297–547

  5. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CUN - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    7h 55m
    $383–772

  6. Fly to Tampa, bus

    1. Fly from Cancún International Airport (CUN) to Tampa (TPA)plane plane CUN - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    9h 37m
    $555–874

  7. Bus #2

    1. Take the bus from Cancún to Cárdenasbus bus
    2. Take the bus from Cárdenas to Reynosabus bus
    3. Take the bus from McAllen Central Station to Houston Bus Stationbus bus
    4. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    2d 22h
    $505–732

Cancún International Airport (CUN) to Ft. Myers (RSW) flights

Calendar38Weekly Planes
Duration6h 43mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Cancún to Sanibel.ExpandLaunch map view
  • Distance: 528.2 mi
  • Duration: 7h 42m

What companies run services between Cancún, Mexico and Sanibel, FL, USA?

Southwest Airlines, Delta, and two other airlines fly from Cancún International Airport (CUN) to Ft. Myers (RSW) 5 times a day. Alternatively, you can take a bus from Terminal de Autobuses ADO Cancún to Sanibel via Villahermosa, Reynosa, McAllen Central Station, Houston - Harrisburg Blvd, and Fort Myers in around 2d 22h.

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