There are 3 ways to get from Cancún to Cayo Guillermo by plane, train, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Ignacio Agramonte International Airport, train, taxi
best- Fly from Cancún International Airport (CUN) to Ignacio Agramonte International Airport (CMW)plane CUN - CMW
- Take the train from Camagüey to Moróntrain
- Take the taxi from Morón to Cayo Guillermotaxi
8h 47m$180–742Fly to José Martí International Airport, bus, drive
- Fly from Cancún International Airport (CUN) to José Martí International Airport (HAV)plane CUN - HAV
- Take the bus from Havana Airport to Santa Clarabus
- Take the bus from Santa Clara to Cayo Santa Maríabus
- Drive from Cayo Santa María to Cayo Guillermocar
13h 22m$260–1,198Fly to Abel Santamaría Airport, bus, drive
- Fly from Cancún International Airport (CUN) to Abel Santamaría Airport (SNU)plane CUN - SNU
- Take the bus from Santa Clara to Cayo Santa Maríabus
- Drive from Cayo Santa María to Cayo Guillermocar
16h 41m$182–834
Cancún International Airport (CUN) to Ignacio Agramonte International Airport (CMW) flights
Comparing Your Travel Options
The cheapest way to get from Cancún to Cayo Guillermo is to fly and bus and drive which costs $260 - $1,200 and takes 13h 22m.
The fastest way to get from Cancún to Cayo Guillermo is to fly and train and taxi which takes 8h 47m and costs $180 - $750.
The distance between Cancún and Cayo Guillermo is 1186 km.
It takes approximately 8h 47m to get from Cancún to Cayo Guillermo, including transfers.
Cayo Guillermo is 1h ahead of Cancún. It is currently 6:01 AM in Cancún and 7:01 AM in Cayo Guillermo.
What companies run services between Cancún, Mexico and Cayo Guillermo, Cuba?
There is no direct connection from Cancún to Cayo Guillermo. However, you can take the bus to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Ignacio Agramonte International Airport (CMW), walk to Albaiza, take the bus to Camaguey, walk to Camagüey, take the train to Morón, then take the taxi to Cayo Guillermo. Alternatively, you can take the bus to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to José Martí International Airport (HAV), walk to Havana Airport, take the bus to Santa Clara, take the bus to Cayo Santa María, then drive to Cayo Guillermo.
- Website
- aa.com
Flights from Cancún International Airport to Abel Santamaría Airport via José Martí International Airport, Miami
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $130–900
- Website
- vivaaerobus.com
Flights from Cancún International Airport to Ignacio Agramonte International Airport
- Ave. Duration
- 35 min
- When
- Wednesday
- Estimated price
- $110–650
Flights from Cancún International Airport to José Martí International Airport
- Ave. Duration
- 10 min
- When
- Every day
- Estimated price
- $220–600
Flights from Cancún International Airport to Ignacio Agramonte International Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday
- Estimated price
- $240–900
Flights from Cancún International Airport to José Martí International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $160–230
- Phone
- +53 7 855 5025 / 7 855 5026 / 5 2161205
- [email protected]
- Website
- facebook.com
Train from Camagüey to Morón
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a week
- Estimated price
- $1–3
- Schedules at
- Horario de Buses Cuba
- Normal
- $1
- Climatizado
- $2
- Phone
- +53 59 89 0616
- [email protected]
- Website
- Viazul
Bus from Havana Airport to Santa Clara
- Ave. Duration
- 4h 53m
- Frequency
- Once daily
- Estimated price
- $21–30
- Website
- Viazul
Bus from Santa Clara to Cayo Santa María
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $8–16
- Website
- Viazul
Bus from Santa Clara to Cayo Santa María
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $8–16
- Website
- Viazul
- Ave. Duration
- 1h 20m
- Estimated price
- $65–80
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from London to Edinburgh, Need to know: Eurostar, and 4 of the smartest ways to explore Australia - to help you get the most out of your next trip.







