There are 5 ways to get from Cancún to Key Largo by plane, shuttle, bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Cancún International Airport to Miami International Airport, shuttle
best- Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane CUN - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 5m$282–597Bus
- Take the bus from Terminal de Autobuses ADO Cancún to Villahermosabus
- Take the bus from Villahermosa to Reynosabus
- Take the bus from Reynosa to Houston Lockwoodbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
3d 5h$496–736Drive 2,940.9 mi
- Drive from Cancún to Key Largocar 2,940.9 mi
2d 7h$537–776Fly Cancún International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane CUN - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 35m$412–807Train to Tulum International Airport, fly to Miami International Airport, shuttle
- Take the train from Estación Tren Maya Cancún Aeropuerto to Estación Tren Maya Tulum Aeropuertotrain
- Fly from Tulum International Airport (TQO) to Miami International Airport (MIA)plane TQO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 23m$414–1,155
Cancún International Airport (CUN) to Miami International Airport (MIA) flights
Comparing Your Travel Options
The cheapest way to get from Cancún to Key Largo is to fly and shuttle which costs $280 - $600 and takes 6h 5m.
The fastest way to get from Cancún to Key Largo is to fly and shuttle which takes 6h 5m and costs $280 - $600.
No, there is no direct bus from Cancún to Key Largo. However, there are services departing from Terminal de Autobuses ADO Cancún and arriving at Key Largo Bus Stop via Villahermosa, Reynosa, Houston - Harrisburg Blvd and Miami Airport Station. The journey, including transfers, takes approximately 3 days 5h.
The distance between Cancún and Key Largo is 597 miles. The road distance is 2958 miles.
The best way to get from Cancún to Key Largo without a car is to bus which takes 3 days 5h and costs $490 - $750.
It takes approximately 6h 5m to get from Cancún to Key Largo, including transfers.
Cancún to Key Largo bus services, operated by ADO, depart from Terminal de Autobuses ADO Cancún station.
Cancún to Key Largo bus services, operated by ADO, arrive at Villahermosa station.
Key Largo is 1h ahead of Cancún. It is currently 4:26 PM in Cancún and 5:26 PM in Key Largo.
Yes, the driving distance between Cancún to Key Largo is 2958 miles. It takes approximately 2 days 7h to drive from Cancún to Key Largo.
What companies run services between Cancún, Mexico and Key Largo, FL, USA?
You can take a bus from Terminal de Autobuses ADO Cancún to Key Largo Bus Stop via Villahermosa, Reynosa, Houston Lockwood, Houston - Harrisburg Blvd, Miami, and Miami Airport Station in around 3d 5h.
- Website
- aa.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $70–410
Flights from Tulum International Airport to Miami International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–550
- Phone
- +52 559 771 1000
- Website
- Booking Tren Maya
Train from Estación Tren Maya Cancún Aeropuerto to Estación Tren Maya Tulum Aeropuerto
- Ave. Duration
- 2h 4m
- Frequency
- Twice daily
- Estimated price
- $13–65
- Website
- Booking Tren Maya
- Special Tourist (INAPAM)
- $13–17
- Local Tourist
- $17–21
- National Tourist
- $25–31
- International Tourist
- $30–45
- National Premier
- $40–50
- International Premier
- $55–65
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
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Booking & Getting There
There are 341+ hotels available in Key Largo.

