Rome2Rio

How to get fromCancún to St. Louisby plane, train, bus, taxi, bus (Flixbus, Greyhound), car, or bus (Amtrak, Flixbus)

Find Transport to St. Louis

See all options

There are 6 ways to get from Cancún to St. Louis by plane, train, bus, taxi, bus (Flixbus, Greyhound), car, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Cancún International Airport (CUN) to Lambert–St. Louis International Airport (STL)plane plane CUN - STL
    5h 53m
    $165–760

  2. Train, bus, taxi

    1. Take the train from Estación Tren Maya Cancún Aeropuerto to Estación Tren Maya Palenquetrain train
    2. Take the bus from Palenque to Villahermosabus bus
    3. Take the taxi from Villahermosa to Cárdenastaxi taxi
    4. Take the bus from Cárdenas to Monterreybus bus
    5. Take the bus from Monterrey to San Antoniobus bus
    6. Take the train from San Antonio Station to St. Louistrain train
    2d 18h
    $696–2,557

  3. Bus via Dallas

    1. Take the bus from Terminal de Autobuses ADO Cancún to Terminal Central de Autobuses del Nortebus bus
    2. Take the bus from Terminal Central de Autobuses del Norte to Dallasbus bus
    3. Take the bus from Downtown Dallas / Deep Ellum to Oklahoma City Bus Stationbus bus
    4. Take the bus from Oklahoma City Bus Station to St Louis Bus Stationbus bus
    2d 22h
    $413–673

  4. Drive  2,507.5 mi

    1. Drive from Cancún to St. Louiscar car 2,507.5 mi
    47h 4m
    $458–661

  5. Bus

    1. Take the bus from Terminal de Autobuses ADO Cancún to Terminal Central de Autobuses del Nortebus bus
    2. Take the bus from Terminal Central de Autobuses del Norte to San Luis de la Pazbus bus
    3. Take the bus from Tornado Bus Co - San Luis de la Paz to Marathon Gas Station - Marionbus bus
    4. Take the bus from Carbondale to St. Louisbus bus
    3d
    $444–693

  6. Bus, train

    1. Take the bus from Terminal de Autobuses ADO Cancún to Terminal Central de Autobuses del Nortebus bus
    2. Take the bus from Terminal Central de Autobuses del Norte to San Marcosbus bus
    3. Take the train from San Marcos Amtrak to St. Louistrain train
    3d 1h
    $518–1,083

Cancún International Airport (CUN) to Lambert–St. Louis International Airport (STL) flights

Calendar56Weekly Planes
Duration4h 53mAverage Duration
Ticket$160Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cancún to St. Louis.ExpandLaunch map view
  • Distance: 1,259.5 mi
  • Duration: 5h 53m

What companies run services between Cancún, Mexico and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Cancún International Airport (CUN) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Terminal de Autobuses ADO Cancún to St Louis Bus Station via Terminal Central de Autobuses del Norte, Dallas, Downtown Dallas / Deep Ellum, and Oklahoma City Bus Station in around 2d 22h.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There