Rome2Rio

How to get fromCanton to Knoxvilleby plane, bus (Flixbus), car, bus, or train

Find Transport to Knoxville

See all options

There are 7 ways to get from Canton to Knoxville by plane, bus (Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Akron

    best
    1. Fly from Akron (CAK) to Mcghee Tyson Airport (TYS)plane plane CAK - TYS
    6h 11m
    $191–819

  2. Drive 484.6 mi

    cheapest
    1. Drive from Canton to Knoxvillecar car 484.6 mi
    8h 10m
    $89–128

  3. Bus via Farragut

    1. Take the bus from Cornerstone Transit Center to Robert K Pfaff Transit Center - Akronbus bus 081
    2. Take the bus from Robert K Pfaff Transit Center - Akron to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    24h 36m
    $261–416

  4. Bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Canton to Clevelandbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Mcghee Tyson Airport (TYS)plane plane CLE - TYS
    7h
    $217–1,013

  5. Bus

    1. Take the bus from Cornerstone Transit Center to Robert K Pfaff Transit Center - Akronbus bus 081
    2. Take the bus from Robert K Pfaff Transit Center - Akron to New York Midtownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    24h 37m
    $216–326

  6. Bus, train

    1. Take the bus from Canton to Clevelandbus bus
    2. Take the train from Cleveland Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    29h 32m
    $337–613

  7. Bus via Columbus

    1. Take the bus from Canton Ohio Sarta Transit Station to Columbus, Ohio Greyhound Stationbus bus
    2. Take the bus from Columbus, OH to New York, NYbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    31h 15m
    $254–285

Akron (CAK) to Mcghee Tyson Airport (TYS) flights

Calendar48Weekly Planes
Duration5h 15mAverage Duration
Ticket$135Cheapest Price
See schedules

Questions & Answers

Map of how to get from Canton to Knoxville.ExpandLaunch map view
  • Distance: 403.6 mi
  • Duration: 6h 11m

What companies run services between Canton, OH, USA and Knoxville, TN, USA?

American Airlines and United Airlines fly from Akron (CAK) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from Cornerstone Transit Center to Knoxville via Robert K Pfaff Transit Center - Akron, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 24h 36m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers