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How to get fromCanton to Mayo Clinicby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 9 ways to get from Canton to Mayo Clinic by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Akron to Rochester

    best
    1. Fly from Akron (CAK) to Rochester (RST)plane plane CAK - RST
    6h 58m
    $73–432

  2. Bus via Milwaukee

    1. Take the bus from Cornerstone Transit Center to Robert K Pfaff Transit Center - Akronbus bus 081
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    19h 13m
    $141–279

  3. Bus, train

    1. Take the bus from Canton to Clevelandbus bus
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    20h 53m
    $257–580

  4. Drive 714.4 mi

    1. Drive from Canton to Mayo Cliniccar car 714.4 mi
    12h 43m
    $131–189

  5. Bus to Cleveland-Hopkins International Airport, fly to Rochester

    1. Take the bus from Canton to Clevelandbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Rochester (RST)plane plane CLE - RST
    8h 11m
    $93–543

  6. Bus to Cleveland-Hopkins International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Canton to Clevelandbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Minneapolis–Saint Paul International Airport (MSP)plane plane CLE - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 4m
    $614–1,095

  7. Bus to John Glenn Columbus International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Canton Ohio Sarta Transit Station to John Glenn Columbus Intnl Airport (CMH)bus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Minneapolis–Saint Paul International Airport (MSP)plane plane CMH - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 59m
    $514–1,108

  8. Bus, train via Madison

    1. Take the bus from Canton to Clevelandbus bus
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    19h 46m
    $184–400

  9. Bus

    1. Take the bus from Canton to Clevelandbus bus
    2. Take the bus from Cleveland to Chicagobus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    20h 8m
    $116–252

Canton to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration19h 13mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Canton to Mayo Clinic.ExpandLaunch map view
  • Distance: 621.2 mi
  • Duration: 6h 58m

What companies run services between Canton, OH, USA and Mayo Clinic, MN, USA?

American Airlines and United Airlines fly from Akron (CAK) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Cornerstone Transit Center to Mayo Clinic via Robert K Pfaff Transit Center - Akron, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 19h 13m.

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Train operators
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