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How to get fromCape Cod to Buffaloby taxi, plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

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There are 7 ways to get from Cape Cod to Buffalo by taxi, plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    6h 35m
    $264–909

  2. Bus

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus Bz 0947 / ...
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 49m
    $88–178

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    16h 49m
    $172–498

  4. Drive 517.1 mi

    1. Drive from Cape Cod to Buffalocar car 517.1 mi
    9h 8m
    $95–137

  5. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    7h 13m
    $101–633

  6. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 28m
    $100–622

  7. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    16h 23m
    $109–173

Cape Cod to Buffalo by bus

Calendar7Weekly Buses
Duration13h 49mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Buffalo.ExpandLaunch map view
  • Distance: 496 mi
  • Duration: 6h 35m

What companies run services between Cape Cod, MA, USA and Buffalo, NY, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Buffalo via Hyannis Transportation Center, Hyannis, and Boston in around 13h 49m. Alternatively, American Airlines, Cape Air, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF) 4 times a day.

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