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How to get fromCape Cod to Charlestonby taxi, plane, bus, train, or car

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There are 7 ways to get from Cape Cod to Charleston by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Charleston International Airport (CHS)plane plane PVC - CHS
    6h 51m
    $294–932

  2. Fly from Barnstable Municipal Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    8h 10m
    $113–603

  3. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    23h 5m
    $284–1,235

  4. Drive  973.4 mi

    1. Drive from Cape Cod to Charlestoncar car 973.4 mi
    18h 31m
    $178–257

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    7h 51m
    $630–992

  6. Bus, train via N. Charleston SuperStop

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    24h 51m
    $251–509

  7. Bus, train via Edison

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Metropark Amtrak Stationtrain train
    3. Take the train from Metropark Amtrak Station to Charleston Amtrak Stationtrain train
    26h 56m
    $266–1,199

Cape Cod to Charleston by bus and train

Calendar14Weekly Services
Duration24h 51mAverage Duration
Ticket$251Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to Charleston.ExpandLaunch map view
  • Distance: 890.2 mi
  • Duration: 6h 51m

What companies run services between Cape Cod, MA, USA and Charleston, SC, USA?

Cape Air, JetBlue Airways, and two other airlines fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) once daily.

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