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How to get fromCape Cod to Charlestonby taxi, plane, train (Amtrak), car, bus, or train

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There are 7 ways to get from Cape Cod to Charleston by taxi, plane, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Provincetown Municipal Airport, fly

    best
    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Charleston International Airport (CHS)plane plane PVC - CHS
    6h 53m
    $264–732

  2. Fly from Barnstable Municipal Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    8h 21m
    $108–558

  3. Train

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    24h 11m
    $318–1,295

  4. Drive 973.4 mi

    1. Drive from Cape Cod to Charlestoncar car 973.4 mi
    18h 30m
    $178–257

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    8h 9m
    $633–995

  6. Bus, train via New York

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    25h 9m
    $294–577

  7. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Metropark Amtrak Stationtrain train
    3. Take the train from Metropark Amtrak Station to Charleston Amtrak Stationtrain train
    27h 21m
    $319–1,262

Cape Cod to Charleston by bus and train

Calendar14Weekly Services
Duration25h 9mAverage Duration
Ticket$294Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Charleston.ExpandLaunch map view
  • Distance: 890.2 mi
  • Duration: 6h 53m

What companies run services between Cape Cod, MA, USA and Charleston, SC, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Charleston via Cape Cod Hospital, Hyannis, South Station, Boston, Ny Moynihan Train Hall At Penn Station, and Charleston Amtrak Station in around 24h 11m. Alternatively, Cape Air, JetBlue Airways, and two other airlines fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) 4 times a day.

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