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How to get fromCape Cod to Charlestonby plane, bus, train, car, or taxi

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There are 8 ways to get from Cape Cod to Charleston by plane, bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    8h 55m
    $113–603

  2. Bus, train via Washington

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train
    22h 53m
    $551–859

  3. Drive  973.4 mi

    1. Drive from Cape Cod to Charlestoncar car 973.4 mi
    18h 31m
    $178–257

  4. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    8h 6m
    $117–628

  5. Taxi to Provincetown Municipal Airport, fly

    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Charleston International Airport (CHS)plane plane PVC - CHS
    8h 1m
    $314–1,032

  6. Bus, train to Theodore Francis Green State Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Charleston International Airport (CHS)plane plane PVD - CHS
    10h 29m
    $205–743

  7. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    23h 5m
    $494–1,465

  8. Bus, train #2

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    25h 11m
    $461–739

Cape Cod to Charleston by bus and train

Calendar14Weekly Services
Duration22h 53mAverage Duration
Ticket$551Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to Charleston.ExpandLaunch map view
  • Distance: 829.7 mi
  • Duration: 8h 55m

What companies run services between Cape Cod, MA, USA and Charleston, SC, USA?

American Airlines, United Airlines, and three other airlines fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) 4 times a day.

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