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How to get fromCape Cod to Columbiaby bus, train, plane, bus (Flixbus), car, or bus (Greyhound)

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There are 12 ways to get from Cape Cod to Columbia by bus, train, plane, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train to Theodore Francis Green State Airport, fly to Columbia

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Columbia (CAE)plane plane PVD - CAE
    11h 30m
    $113–453

  2. Fly Barnstable Municipal Airport to Columbia

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Columbia (CAE)plane plane HYA - CAE
    17h 52m
    $93–483

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Columbia Stationtrain train
    21h 56m
    $277–605

  4. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Columbia, SCbus bus Nyc
    24h 31m
    $154–227

  5. Drive  951 mi

    1. Drive from Cape Cod to Columbiacar car 951 mi
    17h 13m
    $174–251

  6. Bus to Boston Logan Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane plane BOS - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus
    11h 57m
    $214–493

  7. Bus to Boston Logan Airport, fly to Raleigh-Durham International Airport, train

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Raleigh-Durham International Airport (RDU)plane plane BOS - RDU
    3. Take the train from Cary to Columbia Stationtrain train
    12h 37m
    $224–1,066

  8. Bus, train, train to Laguardia Airport, fly to Columbia

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Stamford Amtrak Stationtrain train
    3. Take the train from Stamford to 125th Street - Harlemtrain train
    4. Fly from Laguardia Airport (LGA) to Columbia (CAE)plane plane LGA - CAE
    12h 30m
    $172–1,252

  9. Bus to Boston Logan Airport, fly to Charleston International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    3. Take the bus from Charleston Bus Station to Sumter Bus Stopbus bus
    4. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus
    16h 10m
    $660–1,051

  10. Bus, train to Theodore Francis Green State Airport, fly to Charlotte Douglas International Airport

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Charlotte Douglas International Airport (CLT)plane plane PVD - CLT
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus
    14h 5m
    $182–674

  11. Bus, train via New York

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain train
    4. Take the train from Washington Union Station to Columbia Stationtrain train
    22h 6m
    $267–1,225

  12. Bus via Charlotte

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    5. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Gervais Northbus bus 44
    28h 55m
    $175–352

Cape Cod to Columbia by bus and train

Calendar7Weekly Services
Duration21h 56mAverage Duration
Ticket$277Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Columbia.ExpandLaunch map view
  • Distance: 893.1 mi
  • Duration: 11h 30m

What companies run services between Cape Cod, MA, USA and Columbia, SC, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Sumter Laurel South via Hyannis Transportation Center, Boston, South Station, Boston, NYC Downtown, New York, NY, Columbia, SC, and Broad Marley South in around 24h 31m. Alternatively, Cape Air, JetBlue Airways, and American Airlines fly from Barnstable Municipal Airport (HYA) to Columbia (CAE) 3 times a week.

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