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How to get fromCape Cod to La Crosseby bus, plane, train, bus (Flixbus, Greyhound), or car

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There are 9 ways to get from Cape Cod to La Crosse by bus, plane, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to La Crosse

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to La Crosse (LSE)plane plane BOS - LSE
    10h 4m
    $133–549

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    32h 10m
    $342–805

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to La Crossebus bus
    36h 54m
    $260–402

  4. Drive  1,312.5 mi

    1. Drive from Cape Cod to La Crossecar car 1,312.5 mi
    22h 38m
    $240–346

  5. Bus, train to Theodore Francis Green State Airport, fly to La Crosse

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to La Crosse (LSE)plane plane PVD - LSE
    13h 4m
    $137–544

  6. Bus to Boston Logan Airport, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Dane County Regional Airport-Truax Field (MSN)plane plane BOS - MSN
    3. Take the bus from Madison to La Crossebus bus
    11h 11m
    $191–833

  7. Bus to Boston Logan Airport, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Minneapolis–Saint Paul International Airport (MSP)plane plane BOS - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    11h 39m
    $426–1,104

  8. Bus to Boston Logan Airport, fly to General Mitchell International Airport, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)plane plane BOS - MKE
    3. Take the train from Milwaukee to La Crosse Amtrak Stationtrain train
    11h 47m
    $711–2,060

  9. Bus, train via Madison

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    33h 48m
    $337–745

Cape Cod to La Crosse by bus and train

Calendar7Weekly Services
Duration32h 10mAverage Duration
Ticket$342Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to La Crosse.ExpandLaunch map view
  • Distance: 1,112 mi
  • Duration: 10h 4m

What companies run services between Cape Cod, MA, USA and La Crosse, WI, USA?

You can take a bus from Town Hall Lawton Bus Shelter to La Crosse via Hyannis Transportation Center, Boston, South Station, Boston, New York Midtown, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 36h 54m.

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