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How to get fromCape Cod to Lexingtonby bus, plane, train, car, bus (Flixbus), or bus (Greyhound)

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There are 8 ways to get from Cape Cod to Lexington by bus, plane, train, car, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Columbia

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Columbia (CAE)plane plane BOS - CAE
    8h 17m
    $125–500

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Columbia, SCbus bus Nyc
    23h 39m
    $205–968

  3. Train, bus

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    26h 40m
    $310–1,275

  4. Drive 961.2 mi

    1. Drive from Cape Cod to Lexingtoncar car 961.2 mi
    17h 25m
    $176–254

  5. Bus to Boston Logan Airport, fly to Charleston International Airport, drive

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    3. Drive from Charleston-Airport-CHS to Lexingtoncar car
    8h 29m
    $637–1,015

  6. Bus, train to Theodore Francis Green State Airport, fly to Columbia

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Columbia (CAE)plane plane PVD - CAE
    10h 38m
    $128–486

  7. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Columbia, SCbus bus Nyc
    24h 23m
    $181–265

  8. Bus via Charlotte

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    27h 21m
    $221–376

Boston Logan Airport (BOS) to Columbia (CAE) flights

Calendar145Weekly Planes
Duration5h 6mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Lexington.ExpandLaunch map view
  • Distance: 888.1 mi
  • Duration: 8h 17m

What companies run services between Cape Cod, MA, USA and Lexington, SC, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Lexington via Hyannis Transportation Center, Boston, South Station, Boston, NYC Downtown, New York, NY, and Columbia, SC in around 24h 23m.

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