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How to get fromCape Cod to Lexingtonby plane, bus, train, car, bus (Flixbus), or bus (Greyhound)

Find Transport to Lexington

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There are 9 ways to get from Cape Cod to Lexington by plane, bus, train, car, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Columbia

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Columbia (CAE)plane plane HYA - CAE
    7h 15m
    $114–496

  2. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Columbia, SCbus bus Nyc
    23h 39m
    $192–958

  3. Bus, train via Charlotte

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    25h 37m
    $285–1,249

  4. Drive  961.2 mi

    1. Drive from Cape Cod to Lexingtoncar car 961.2 mi
    17h 25m
    $176–254

  5. Bus to Boston Logan Airport, fly to Columbia

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Columbia (CAE)plane plane BOS - CAE
    8h 17m
    $127–521

  6. Bus to Boston Logan Airport, fly to Charleston International Airport, drive

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    3. Drive from Charleston-Airport-CHS to Lexingtoncar car
    8h 29m
    $684–1,006

  7. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Columbia, SCbus bus Nyc
    24h 23m
    $182–265

  8. Bus, train via Petersburg

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Durham Amtrak Stationtrain train
    4. Take the bus from Durham to Columbia, SCbus bus Nyc
    26h 51m
    $288–621

  9. Bus via Charlotte

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    27h 21m
    $227–360

Barnstable Municipal Airport (HYA) to Columbia (CAE) flights

Calendar21Weekly Planes
Duration6h 52mAverage Duration
Ticket$87Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to Lexington.ExpandLaunch map view
  • Distance: 810.8 mi
  • Duration: 7h 15m

What companies run services between Cape Cod, MA, USA and Lexington, SC, USA?

American Airlines and United Airlines fly from Barnstable Municipal Airport (HYA) to Columbia (CAE) 3 times a day. Alternatively, you can take a bus from Town Hall Lawton Bus Shelter to Lexington via Hyannis Transportation Center, Boston, South Station, Boston, NYC Downtown, New York, NY, and Columbia, SC in around 24h 23m.

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