There are 8 ways to get from Cape Cod to South Carolina by bus, plane, taxi, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Boston Logan Airport, fly to Charlotte Douglas International Airport, taxi
best- Take the bus from Hyannis to Bostonbus
- Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane BOS - CLT
- Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi
7h 5m$225–556Bus, train to Theodore Francis Green State Airport, fly to Charleston International Airport
cheapest- Take the bus from Hyannis to Bostonbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Charleston International Airport (CHS)plane PVD - CHS
9h 53m$125–643Bus, train
- Take the bus from Hyannis to Bostonbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain
23h 5m$494–1,465Drive 973.4 mi
- Drive from Cape Cod to Charlestoncar 973.4 mi
18h 31m$167–241Bus to Boston Logan Airport, fly to Charleston International Airport
- Take the bus from Hyannis to Bostonbus
- Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane BOS - CHS
7h 40m$127–628Bus, train to Theodore Francis Green State Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Hyannis to Bostonbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Greenville–Spartanburg International Airport (GSP)plane PVD - GSP
9h 12m$168–686Bus, train to Theodore Francis Green State Airport, fly to Charlotte Douglas International Airport, taxi
- Take the bus from Hyannis to Bostonbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Charlotte Douglas International Airport (CLT)plane PVD - CLT
- Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi
9h 18m$223–841Bus, train, taxi
- Take the bus from Hyannis Transportation Center to Boston South Busesbus
- Take the bus from Boston to New York Midtownbus
- Take the train from Ny Moynihan Train Hall At Penn Station to Savannah Stationtrain
- Take the taxi from Savannah Station to Bluffton Transfer Centertaxi
- Take the bus from Bluffton Transfer Center to Walmartbus 320
- Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi
31h 41m
Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT) flights
Comparing Your Travel Options
The cheapest way to get from Cape Cod to South Carolina is to drive which costs $160 - $240 and takes 18h 31m.
The fastest way to get from Cape Cod to South Carolina is to bus and fly and taxi which takes 7h 5m and costs $220 - $600.
The distance between Cape Cod and South Carolina is 840 miles. The road distance is 979.1 miles.
The best way to get from Cape Cod to South Carolina without a car is to bus and train which takes 23h 5m and costs $490 - $1,500.
It takes approximately 7h 5m to get from Cape Cod to South Carolina, including transfers.
Yes, the driving distance between Cape Cod to South Carolina is 979 miles. It takes approximately 18h 31m to drive from Cape Cod to South Carolina.
There are 1902+ hotels available in South Carolina.
What companies run services between Cape Cod, MA, USA and South Carolina, USA?
There is no direct connection from Cape Cod to South Carolina. However, you can take the bus to Hyannis Transportation Center, walk to Hyannis, take the bus to Boston, walk to Boston Logan Airport (BOS) airport, fly to Charlotte Douglas International Airport (CLT), then take the taxi to Rock Hill. Alternatively, you can take a bus from Town Hall Lawton Bus Shelter to Charleston via Hyannis Transportation Center, Hyannis, Boston, Boston, Ny Moynihan Train Hall At Penn Station, and Charleston Amtrak Station in around 23h 5m.
- Website
- aa.com
Flights from Boston Logan Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $130–700
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 5h 10m
- When
- Monday to Saturday
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 24m
- When
- Every day
- Estimated price
- $120–700
Flights from Theodore Francis Green State Airport to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Theodore Francis Green State Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Charleston International Airport via Philadelphia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Boston Logan Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 22m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $120–700
Flights from Theodore Francis Green State Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Boston Logan Airport to Charlotte Douglas International Airport via Washington Dulles
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Boston Logan Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Charlotte Douglas International Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
- Website
- delta.com
Flights from Boston Logan Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Charleston International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 33m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $220–1,300
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Pittsburgh
- Ave. Duration
- 5h 13m
- When
- Thursday and Sunday
- Estimated price
- $220–1,300
Flights from Theodore Francis Green State Airport to Charleston International Airport
- Ave. Duration
- 2h 30m
- When
- Thursday, Sunday, Saturday, Monday, and Friday
- Estimated price
- $200–1,200
- Website
- jetblue.com
Flights from Boston Logan Airport to Charleston International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Station
- Ave. Duration
- 14h 18m
- Frequency
- Twice daily
- Estimated price
- $400–650
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Savannah Station
- Ave. Duration
- 16h 13m
- Frequency
- Twice daily
- Estimated price
- $450–700
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $15–26
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $15–26
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
Bus from Hyannis to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
- Phone
- +1 (508) 746-0378
- [email protected]
- Website
- Plymouth & Brockton
Bus from Hyannis Transportation Center to Boston South Buses
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
- Phone
- 843-757-5782
- Website
- Palmetto Breeze Transit
Bus from Bluffton Transfer Center to Walmart
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Schedules at
- Palmetto Breeze Transit
- Ave. Duration
- 39 min
- Estimated price
- $80–140
Charlotte Taxi Service
- Phone
- +1 704-464-9191
- Website
- charlottetaxiservice.com
Crown Cab Charlotte
- Phone
- +1 704-334-6666
- Website
- crowncabinc.com
Yellow Cab of Charlotte
- Phone
- +1 704-444-4444
Charlotte Taxi Service
- Phone
- +1 704-464-9191
- Website
- charlottetaxiservice.com
Crown Cab Charlotte
- Phone
- +1 704-334-6666
- Website
- crowncabinc.com
Yellow Cab of Charlotte
- Phone
- +1 704-444-4444
East Side Taxi
- Phone
- +19125722213
Elite Taxi
- Phone
- +1 706-513-3721
- Website
- taxisavannah.net
Yellow Cab of Savannah
- Phone
- +1 912-236-1133
- Website
- yellowcabsavannah.com
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