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How to get fromCape Cod to South Carolinaby bus, plane, taxi, train (Amtrak), car, or train

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There are 9 ways to get from Cape Cod to South Carolina by bus, plane, taxi, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Charlotte Douglas International Airport, taxi

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane plane BOS - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    6h 57m
    $235–515

  2. Fly Barnstable Municipal Airport to Charleston International Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    7h 39m
    $103–553

  3. Train

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    24h 8m
    $300–1,280

  4. Drive 973.4 mi

    1. Drive from Cape Cod to Charlestoncar car 973.4 mi
    18h 31m
    $178–257

  5. Bus to Boston Logan Airport, fly to Charleston International Airport

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    7h 36m
    $617–987

  6. Bus, train to Theodore Francis Green State Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Charlotte Douglas International Airport (CLT)plane plane PVD - CLT
    4. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    9h 13m
    $203–701

  7. Bus, train to Theodore Francis Green State Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Greenville–Spartanburg International Airport (GSP)plane plane PVD - GSP
    9h 17m
    $318–996

  8. Bus, train to Theodore Francis Green State Airport, fly to Charleston International Airport

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Charleston International Airport (CHS)plane plane PVD - CHS
    9h 58m
    $135–603

  9. Bus, train, taxi

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Savannah Stationtrain train
    4. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    5. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    6. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    31h 41m

Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT) flights

Calendar87Weekly Planes
Duration2h 47mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to South Carolina.ExpandLaunch map view
  • Distance: 835.4 mi
  • Duration: 6h 57m

What companies run services between Cape Cod, MA, USA and South Carolina, USA?

You can take a bus from Town Hall Lawton Bus Shelter to Charleston via Hyannis Transportation Center, Hyannis, South Station, Boston, Ny Moynihan Train Hall At Penn Station, and Charleston Amtrak Station in around 24h 8m. Alternatively, Cape Air, JetBlue Airways, and Delta fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) twice daily.

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