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How to get fromCape Coral to Buffaloby plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

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There are 7 ways to get from Cape Coral to Buffalo by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Buffalo Niagara International Airport

    best
    1. Fly from Ft. Myers (RSW) to Buffalo Niagara International Airport (BUF)plane plane RSW - BUF
    6h 34m
    $214–984

  2. Bus to Fort Lauderdale–Hollywood International Airport, fly to Buffalo Niagara International Airport

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Buffalo Niagara International Airport (BUF)plane plane FLL - BUF
    9h 3m
    $194–867

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Buffalobus bus
    37h 55m
    $246–478

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the train from Orlando to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    45h 45m
    $492–1,067

  5. Drive 1,332.2 mi

    1. Drive from Cape Coral to Buffalocar car 1,332.2 mi
    23h 6m
    $244–352

  6. Bus to Tampa, fly to Buffalo Niagara International Airport

    1. Take the bus from Fort Myers to Tampa Airportbus bus
    2. Fly from Tampa (TPA) to Buffalo Niagara International Airport (BUF)plane plane TPA - BUF
    7h 21m
    $297–898

  7. Taxi to Punta Gorda Airport, fly to Niagara Falls International Airport

    1. Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Niagara Falls International Airport (IAG)plane plane PGD - IAG
    6h 15m
    $196–582

Cape Coral to Buffalo by bus

Calendar7Weekly Buses
Duration37h 55mAverage Duration
Ticket$246Cheapest Price
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Questions & Answers

Map of how to get from Cape Coral to Buffalo.ExpandLaunch map view
  • Distance: 1,176.9 mi
  • Duration: 6h 34m

What companies run services between Cape Coral, FL, USA and Buffalo, NY, USA?

JetBlue Airways, Southwest Airlines, and two other airlines fly from Ft. Myers (RSW) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to Buffalo via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station, and Cleveland Bus Station in around 37h 55m.

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