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How to get fromCape Coral to Chicagoby plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

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There are 9 ways to get from Cape Coral to Chicago by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Chicago Midway International Airport

    best
    1. Fly from Ft. Myers (RSW) to Chicago Midway International Airport (MDW)plane plane RSW - MDW
    6h 23m
    $116–560

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    32h 30m
    $212–348

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Chicago Union Stationtrain train Floridian
    47h 22m
    $976–1,642

  4. Drive  1,230.3 mi

    1. Drive from Cape Coral to Chicagocar car 1,230.3 mi
    22h 28m
    $225–325

  5. Fly Ft. Myers to Chicago O'Hare International Airport

    1. Fly from Ft. Myers (RSW) to Chicago O'Hare International Airport (ORD)plane plane RSW - ORD
    6h 49m
    $116–380

  6. Taxi to Punta Gorda Airport, fly to Chicago Midway International Airport

    1. Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Chicago Midway International Airport (MDW)plane plane PGD - MDW
    4h 11m
    $176–554

  7. Bus to Sarasota–Bradenton International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Chicago Midway International Airport (MDW)plane plane SRQ - MDW
    9h
    $156–728

  8. Bus to Sarasota–Bradenton International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Chicago O'Hare International Airport (ORD)plane plane SRQ - ORD
    9h 32m
    $126–628

  9. Bus to Tampa, fly to Chicago Midway International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Chicago Midway International Airport (MDW)plane plane TPA - MDW
    10h 37m
    $126–446

Cape Coral to Chicago by bus

Calendar5Weekly Buses
Duration32h 30mAverage Duration
Ticket$212Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Coral to Chicago.ExpandLaunch map view
  • Distance: 1,135.4 mi
  • Duration: 6h 23m

What companies run services between Cape Coral, FL, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Ft. Myers (RSW) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to Chicago Bus Station via Fort Myers Bus Stop, Tampa Bus Station, and Atlanta Bus Station in around 32h 30m.

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