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How to get fromCape Coral to Columbiaby plane, bus, train, bus (Flixbus, Greyhound), or car

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There are 4 ways to get from Cape Coral to Columbia by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Ft. Myers (RSW) to Columbia (CAE)plane plane RSW - CAE
    7h 57m
    $226–1,207
  2. Bus

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    4. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    20h 46m
    $100–195
  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Columbia Stationtrain train Floridian
    17h 48m
    $186–392
  4. Drive 587.5 mi

    1. Drive from Cape Coral to Columbiacar car 587.5 mi
    10h 22m
    $108–155

Cape Coral to Columbia by bus and train

Calendar7Weekly Services
Duration17h 48mAverage Duration
Ticket$186Cheapest Price
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Questions & Answers

What companies run services between Cape Coral, FL, USA and Columbia, SC, USA?

Delta, American Airlines, and United Airlines fly from Ft. Myers (RSW) to Columbia (CAE) hourly. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to Assembly Senate North via Fort Myers Bus Stop, Orlando Bus Station, Jacksonville, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 20h 46m.

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