There are 6 ways to get from Cape Coral to Des Moines by taxi, plane, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Punta Gorda Airport, fly
best- Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi
- Fly from Punta Gorda Airport (PGD) to Des Moines (DSM)plane PGD - DSM
3h 57m$289–979Fly from Ft. Myers
cheapest- Fly from Ft. Myers (RSW) to Des Moines (DSM)plane RSW - DSM
6h 18m$240–1,026Bus
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Des Moinesbus
36h 55m$244–473Bus, train
- Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus
- Take the train from Orlando to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
2d 6h$648–1,377Drive 1,444.5 mi
- Drive from Cape Coral to Des Moinescar 1,444.5 mi
25h 42m$264–381Bus to Sarasota–Bradenton International Airport, fly
- Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus
- Fly from Sarasota–Bradenton International Airport (SRQ) to Des Moines (DSM)plane SRQ - DSM
8h 59m$252–1,148
Cape Coral to Des Moines by bus
Questions & Answers
The cheapest way to get from Cape Coral to Des Moines is to bus which costs $240 - $480 and takes 36h 55m.
The fastest way to get from Cape Coral to Des Moines is to taxi and fly which takes 3h 57m and costs $280 - $1,000.
No, there is no direct bus from Cape Coral to Des Moines. However, there are services departing from Cc Pwky @ Vincennes St and arriving at Des Moines via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 36h 55m.
The distance between Cape Coral and Des Moines is 1250 miles. The road distance is 1452.9 miles.
The best way to get from Cape Coral to Des Moines without a car is to bus which takes 36h 55m and costs $240 - $480.
It takes approximately 3h 57m to get from Cape Coral to Des Moines, including transfers.
Cape Coral to Des Moines bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Cape Coral to Des Moines is to bus which takes 36h 55m and costs $240 - $480. Alternatively, you can fly, which costs $240 - $1,100 and takes 6h 18m.
Cape Coral to Des Moines bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
Des Moines is 1h behind Cape Coral. It is currently 5:06 PM in Cape Coral and 4:06 PM in Des Moines.
What companies run services between Cape Coral, FL, USA and Des Moines, IA, USA?
You can take a bus from Cc Pwky @ Vincennes St to Des Moines via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station, and St Louis Bus Station in around 36h 55m. Alternatively, Allegiant Air, Delta, and three other airlines fly from Ft. Myers (RSW) to Des Moines (DSM) every 2 hours.
- Website
- delta.com
Flights from Ft. Myers to Des Moines via Atlanta
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Ft. Myers to Des Moines via Detroit
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $270–1,200
Flights from Sarasota–Bradenton International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Sarasota–Bradenton International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $280–1,200
- Website
- southwest.com
Flights from Ft. Myers to Des Moines via Chicago Midway
- Ave. Duration
- 5h 26m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $240–1,100
Flights from Sarasota–Bradenton International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- $250–1,100
- Website
- allegiantair.com
Flights from Punta Gorda Airport to Des Moines
- Ave. Duration
- 3h 5m
- When
- Thursday and Sunday
- Estimated price
- $180–850
Flights from Ft. Myers to Des Moines
- Ave. Duration
- 3h 15m
- When
- Friday
- Estimated price
- $220–1,000
Flights from Sarasota–Bradenton International Airport to Des Moines
- Ave. Duration
- 2h 58m
- When
- Saturday
- Estimated price
- $220–1,100
- Website
- united.com
Flights from Ft. Myers to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Sarasota–Bradenton International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $250–1,200
- Website
- aa.com
Flights from Ft. Myers to Des Moines via Charlotte
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Sarasota–Bradenton International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Orlando to Chicago Union Station
- Ave. Duration
- 38h 55m
- Frequency
- Once daily
- Estimated price
- $550–1,200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Bus from Tampa Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $75–130
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 21m
- Frequency
- 5 times a week
- Estimated price
- $90–160
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 1h 40m
- Frequency
- 3 times a day
- Estimated price
- $11–20
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Ave. Duration
- 41 min
- Estimated price
- $90–110
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
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More Questions & Answers
Yes, the driving distance between Cape Coral to Des Moines is 1453 miles. It takes approximately 25h 42m to drive from Cape Coral to Des Moines.
There are 265+ hotels available in Des Moines.






