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How to get fromCape Coral to Florenceby plane, bus (Flixbus), bus, train, or car

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There are 4 ways to get from Cape Coral to Florence by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Ft. Myers (RSW) to Florence Regional Airport (FLO)plane plane RSW - FLO
    7h 4m
    $104–478
  2. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Florencebus bus FlixBus N2472
    16h 36m
    $122–201
  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the train from Winter Park Amtrak Station to Florence Stationtrain train Silver Meteor
    18h 46m
    $188–385
  4. Drive 605.8 mi

    1. Drive from Cape Coral to Florencecar car 605.8 mi
    10h 40m
    $111–160

Cape Coral to Florence by bus and train

Calendar7Weekly Services
Duration18h 46mAverage Duration
Ticket$188Cheapest Price
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Questions & Answers

What companies run services between Cape Coral, FL, USA and Florence, SC, USA?

American Airlines flies from Ft. Myers (RSW) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to Florence via Fort Myers Bus Stop, Orlando Bus Station, and Florence in around 16h 36m.

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