There are 3 ways to get from Cape Coral to Florida Keys by ferry, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
6h 12m$167–177Drive 259.3 mi
cheapest- Drive from Cape Coral to Florida Keyscar 259.3 mi
5h 33m$48–69Bus
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus FlixBus 2421
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
11h 5m$50–82
Cape Coral to Florida Keys by bus and foot
Comparing Your Travel Options
The cheapest way to get from Cape Coral to Florida Keys is to drive which costs $45 - $70 and takes 5h 33m.
The fastest way to get from Cape Coral to Florida Keys is to drive which takes 5h 33m and costs $45 - $70.
No, there is no direct bus from Cape Coral to Florida Keys. However, there are services departing from Cc Pwky @ Vincennes St and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Fort Myers Bus Stop, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 11h 5m.
No, there is no direct ferry from Cape Coral to Florida Keys. However, there are services departing from Fort Myers Beach, FL and arriving at Key West, FL via . The journey, including transfers, takes approximately 6h 12m.
The distance between Cape Coral and Florida Keys is 167 miles. The road distance is 260.8 miles.
The best way to get from Cape Coral to Florida Keys without a car is to ferry which takes 6h 12m and costs $165 - $180.
It takes approximately 6h 12m to get from Cape Coral to Florida Keys, including transfers.
Cape Coral to Florida Keys bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Cape Coral to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Cape Coral to Florida Keys is 261 miles. It takes approximately 5h 33m to drive from Cape Coral to Florida Keys.
What companies run services between Cape Coral, FL, USA and Florida Keys, FL, USA?
Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to Florida Keys via Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 11h 5m.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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Booking & Getting There
There are 922+ hotels available in Florida Keys.







