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How to get fromCape Coral to Florida Panhandleby bus, car, or plane

Find Transport to Florida Panhandle

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There are 9 ways to get from Cape Coral to Florida Panhandle by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Fort Myers 7-11 to Tallahassee, FLbus bus Miami
    2. Drive from Tallahassee, FL to Florida Panhandlecar car
    9h 41m
    $156–260

  2. Bus, drive via Tampa

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Drive from Tallahassee to Florida Panhandlecar car
    12h 56m
    $68–129

  3. Drive 419.5 mi

    1. Drive from Cape Coral to Florida Panhandlecar car 419.5 mi
    8h 5m
    $77–111

  4. Fly Ft. Myers to Tallahassee, drive

    1. Fly from Ft. Myers (RSW) to Tallahassee (TLH)plane plane RSW - TLH
    2. Drive from Tallahassee (TLH) to Florida Panhandlecar car
    8h 10m
    $124–620

  5. Bus, drive via Gainesville

    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville to Tallahasseebus bus
    4. Drive from Tallahassee to Florida Panhandlecar car
    10h 49m
    $130–215

  6. Fly Ft. Myers to Northwest Florida Beaches International Airport, drive

    1. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Florida Panhandlecar car
    8h 16m
    $104–500

  7. Fly Ft. Myers to Dothan Regional Airport, drive

    1. Fly from Ft. Myers (RSW) to Dothan Regional Airport (DHN)plane plane RSW - DHN
    2. Drive from Dothan Regional Airport (DHN) to Florida Panhandlecar car
    8h 31m
    $102–487

  8. Bus to Miami International Airport, fly to Tallahassee, drive

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Tallahassee (TLH)plane plane MIA - TLH
    3. Drive from Tallahassee (TLH) to Florida Panhandlecar car
    8h 50m
    $102–453

  9. Bus to Fort Lauderdale–Hollywood International Airport, fly to Tallahassee, drive

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Tallahassee (TLH)plane plane FLL - TLH
    3. Drive from Tallahassee (TLH) to Florida Panhandlecar car
    7h 57m
    $242–908

Ft. Myers (RSW) to Tallahassee (TLH) flights

Calendar83Weekly Planes
Duration5h 47mAverage Duration
Ticket$118Cheapest Price
See schedules

Questions & Answers

Map of how to get from Cape Coral to Florida Panhandle.ExpandLaunch map view
  • Distance: 477.1 mi
  • Duration: 9h 41m

What companies run services between Cape Coral, FL, USA and Florida Panhandle, FL, USA?

There is no direct connection from Cape Coral to Florida Panhandle. However, you can take the taxi to Fort Myers 7-11, take the bus to Tallahassee, FL, then drive to Florida Panhandle. Alternatively, you can drive from Cape Coral to Florida Panhandle in around 8h 5m.

Airlines
Bus operators

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