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How to get fromCape Coral to Lake Cityby bus (Flixbus, Greyhound) or car

Find Transport to Lake City

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There are 4 ways to get from Cape Coral to Lake City by bus (Flixbus, Greyhound) or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    9h 12m
    $103–168

  2. Drive 278.5 mi

    cheapest
    1. Drive from Cape Coral to Lake Citycar car 278.5 mi
    5h 21m
    $51–74

  3. Bus via Orlando

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus Greyhound US0630
    11h 50m
    $60–108

  4. Bus via Tampa

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    12h 15m
    $52–92

Cape Coral to Lake City by bus

Calendar14Weekly Buses
Duration11h 50mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Cape Coral to Lake City.ExpandLaunch map view
  • Distance: 317.9 mi
  • Duration: 9h 12m

What companies run services between Cape Coral, FL, USA and Lake City, FL, USA?

You can take a vehicle from Cape Coral to Lake City Bus Station via Fort Myers 7-11, University of South Florida, Gainesville, Rosa Parks RTS Downtown Station, and Gainesville Bus Stop in around 9h 12m.

Operators

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Need to know: Greyhound

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