There are 7 ways to get from Cape Coral to Panama City Beach by plane, bus (Flixbus, Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Ft. Myers to Northwest Florida Beaches International Airport
best- Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane RSW - ECP
7h 16m$144–550Bus
cheapest- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Tallahasseebus
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus
14h 49m$82–150Bus via Gainesville
- Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus
- Take the bus from University of South Florida to Gainesvillebus
- Take the bus from Gainesville to Tallahasseebus
- Take the bus from Tallahassee to Panama City Beach Bus Stationbus
12h 42m$142–236Drive 466.7 mi
- Drive from Cape Coral to Panama City Beachcar 466.7 mi
8h 58m$86–123Fly Ft. Myers to Destin–Fort Walton Beach Airport, drive
- Fly from Ft. Myers (RSW) to Destin–Fort Walton Beach Airport (VPS)plane RSW - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar
8h 14m$108–501Bus to Sarasota–Bradenton International Airport, fly to Northwest Florida Beaches International Airport
- Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus
- Fly from Sarasota–Bradenton International Airport (SRQ) to Northwest Florida Beaches International Airport (ECP)plane SRQ - ECP
10h 58m$158–580Bus to Miami International Airport, fly to Destin–Fort Walton Beach Airport, drive
- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus
- Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane MIA - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar
9h 15m$90–384
Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP) flights
Questions & Answers
The cheapest way to get from Cape Coral to Panama City Beach is to bus which costs $80 - $150 and takes 14h 49m.
The fastest way to get from Cape Coral to Panama City Beach is to fly which takes 7h 16m and costs $140 - $550.
No, there is no direct bus from Cape Coral to Panama City Beach station. However, there are services departing from Fort Myers 7-11 and arriving at Panama City Beach Bus Station via University of South Florida, Gainesville and Tallahassee. The journey, including transfers, takes approximately 12h 42m.
The distance between Cape Coral and Panama City Beach is 399 miles. The road distance is 469.4 miles.
The best way to get from Cape Coral to Panama City Beach without a car is to bus via Gainesville which takes 12h 42m and costs $140 - $240.
It takes approximately 7h 16m to get from Cape Coral to Panama City Beach, including transfers.
Cape Coral to Panama City Beach bus services, operated by RedCoach, depart from Fort Myers 7-11 station.
The best way to get from Cape Coral to Panama City Beach is to fly which takes 7h 16m and costs $140 - $550. Alternatively, you can bus via Gainesville, which costs $140 - $240 and takes 12h 42m.
Cape Coral to Panama City Beach bus services, operated by RedCoach, arrive at University of South Florida - 3801 USF Holly Dr station.
Panama City Beach is 1h behind Cape Coral. It is currently 3:32 AM in Cape Coral and 2:32 AM in Panama City Beach.
What companies run services between Cape Coral, FL, USA and Panama City Beach, FL, USA?
Delta, Southwest Airlines, and American Airlines fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP) every 3 hours. Alternatively, you can take a vehicle from Cape Coral to Panama City Beach via Fort Myers 7-11, University of South Florida, Gainesville, Tallahassee, and Panama City Beach Bus Station in around 12h 42m.
- Website
- delta.com
Flights from Ft. Myers to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $90–480
Flights from Ft. Myers to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $95–480
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $95–490
Flights from Miami International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $75–390
- Website
- southwest.com
Flights from Ft. Myers to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 5h 27m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $120–600
Flights from Ft. Myers to Northwest Florida Beaches International Airport via St. Louis
- Ave. Duration
- 7h 21m
- When
- Saturday and Sunday
- Estimated price
- $160–700
Flights from Ft. Myers to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 6h 26m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–600
Flights from Ft. Myers to Destin–Fort Walton Beach Airport via St. Louis
- Ave. Duration
- 6h 47m
- When
- Sunday and Saturday
- Estimated price
- $160–700
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 5h 50m
- When
- Monday to Wednesday
- Estimated price
- $120–600
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via St. Louis
- Ave. Duration
- 6h 55m
- When
- Saturday
- Estimated price
- $170–750
- Website
- aa.com
Flights from Ft. Myers to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 4h 56m
- When
- Sunday, Monday, Wednesday, Thursday, and Friday
- Estimated price
- $110–550
Flights from Ft. Myers to Destin–Fort Walton Beach Airport via Charlotte
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $120–550
Flights from Sarasota–Bradenton International Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $120–600
Flights from Miami International Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $55–320
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- RedCoach
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from University of South Florida to Gainesville
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $19–35
- Schedules at
- Flixbus USA
Bus from Gainesville to Tallahassee
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
Bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Center
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- Every 4 hours
- Estimated price
- $24–45
- Schedules at
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Tampa Bus Station to Tallahassee
- Ave. Duration
- 5h 20m
- Frequency
- 4 times a day
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- Greyhound
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More Questions & Answers
Yes, the driving distance between Cape Coral to Panama City Beach is 469 miles. It takes approximately 8h 58m to drive from Cape Coral to Panama City Beach.
There are 4710+ hotels available in Panama City Beach.







