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How to get fromCape Coral to St. Louisby plane, bus (Flixbus, Greyhound), car, taxi, or bus

Find Transport to St. Louis

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There are 7 ways to get from Cape Coral to St. Louis by plane, bus (Flixbus, Greyhound), car, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Lambert–St. Louis International Airport

    best
    1. Fly from Ft. Myers (RSW) to Lambert–St. Louis International Airport (STL)plane plane RSW - STL
    6h 10m
    $126–658

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    27h 40m
    $192–323

  3. Drive  1,114.3 mi

    1. Drive from Cape Coral to St. Louiscar car 1,114.3 mi
    19h 8m
    $197–285

  4. Taxi to Punta Gorda Airport, fly to Midamerica St. Louis Airport

    1. Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Midamerica St. Louis Airport (BLV)plane plane PGD - BLV
    4h 15m
    $195–561

  5. Bus to Sarasota–Bradenton International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    8h 31m
    $128–627

  6. Bus to Tampa, fly to Lambert–St. Louis International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    9h 43m
    $126–589

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL)plane plane FLL - STL
    8h 48m
    $166–741

Cape Coral to St. Louis by bus

Calendar5Weekly Buses
Duration27h 40mAverage Duration
Ticket$192Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Coral to St. Louis.ExpandLaunch map view
  • Distance: 1,010.8 mi
  • Duration: 6h 10m

What companies run services between Cape Coral, FL, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and American Airlines fly from Ft. Myers (RSW) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Cc Pwky @ Vincennes St to St Louis Bus Station via Fort Myers Bus Stop, Tampa Bus Station, and Atlanta Bus Station in around 27h 40m.

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