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How to get fromCape Coral to Tupeloby plane, car, bus (Flixbus, Greyhound), or bus

Find Transport to Tupelo

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There are 6 ways to get from Cape Coral to Tupelo by plane, car, bus (Flixbus, Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Golden Triangle Regional Airport, drive

    best
    1. Fly from Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR)plane plane RSW - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 32m
    $94–472

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tupelobus bus
    22h 37m
    $164–257

  3. Drive  771.1 mi

    1. Drive from Cape Coral to Tupelocar car 771.1 mi
    14h 25m
    $141–204

  4. Fly Ft. Myers to Tupelo Regional Airport

    1. Fly from Ft. Myers (RSW) to Tupelo Regional Airport (TUP)plane plane RSW - TUP
    7h 55m
    $138–673

  5. Bus to Tampa, fly to Birmingham–Shuttlesworth International Airport, drive

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Birmingham–Shuttlesworth International Airport (BHM)plane plane TPA - BHM
    3. Drive from Birmingham-Airport-BHM to Tupelocar car
    11h 6m
    $168–831

  6. Fly Ft. Myers to Memphis, bus

    1. Fly from Ft. Myers (RSW) to Memphis (MEM)plane plane RSW - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    10h 54m
    $204–997

Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR) flights

Calendar21Weekly Planes
Duration6h 51mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Coral to Tupelo.ExpandLaunch map view
  • Distance: 707.5 mi
  • Duration: 8h 32m

What companies run services between Cape Coral, FL, USA and Tupelo, MS, USA?

You can take a bus from Del Prado Blvd S @ Se 47Th St-Nb to Tupelo via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station, and Tupelo in around 22h 37m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Ft. Myers (RSW) to Tupelo Regional Airport (TUP) 3 times a day.

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