There are 5 ways to get from Cape Coral to Tupelo by plane, car, bus (Flixbus, Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Ft. Myers to Golden Triangle Regional Airport, drive
best- Fly from Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR)plane RSW - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
7h 51m$90–441Bus
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tupelobus
21h 57m$162–257Drive 771.1 mi
- Drive from Cape Coral to Tupelocar 771.1 mi
14h 25m$137–197Bus to Tampa, fly to Birmingham–Shuttlesworth International Airport, drive
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Birmingham–Shuttlesworth International Airport (BHM)plane TPA - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
10h 26m$166–821Fly Ft. Myers to Tupelo Regional Airport
- Fly from Ft. Myers (RSW) to Tupelo Regional Airport (TUP)plane RSW - TUP
8h 40m$128–623
Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Cape Coral to Tupelo is to drive which costs $130 - $200 and takes 14h 25m.
The fastest way to get from Cape Coral to Tupelo is to fly and drive which takes 7h 51m and costs $85 - $450.
No, there is no direct bus from Cape Coral to Tupelo. However, there are services departing from Del Prado Blvd S @ Se 47Th St-Nb and arriving at Tupelo via Fort Myers Bus Stop, Tampa Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 21h 57m.
The distance between Cape Coral and Tupelo is 712 miles. The road distance is 775.6 miles.
The best way to get from Cape Coral to Tupelo without a car is to bus which takes 21h 57m and costs $160 - $260.
It takes approximately 7h 51m to get from Cape Coral to Tupelo, including transfers.
Cape Coral to Tupelo bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Cape Coral to Tupelo is to bus which takes 21h 57m and costs $160 - $260. Alternatively, you can fly, which costs $120 - $650 and takes 8h 40m.
Cape Coral to Tupelo bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
Tupelo is 1h behind Cape Coral. It is currently 8:01 AM in Cape Coral and 7:01 AM in Tupelo.
What companies run services between Cape Coral, FL, USA and Tupelo, MS, USA?
You can take a bus from Del Prado Blvd S @ Se 47Th St-Nb to Tupelo via Fort Myers Bus Stop, Tampa Bus Station, Atlanta Bus Station, and Tupelo in around 21h 57m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Ft. Myers (RSW) to Tupelo Regional Airport (TUP) 3 times a day.
- Website
- delta.com
Flights from Ft. Myers to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $75–420
Flights from Tampa to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $130–800
- Website
- contouraviation.com
Flights from Ft. Myers to Tupelo Regional Airport via Nashville
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $110–600
Flights from Ft. Myers to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $160–750
Flights from Ft. Myers to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Tampa to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $120–750
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Atlanta Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 5 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Cape Coral to Tupelo is 776 miles. It takes approximately 14h 25m to drive from Cape Coral to Tupelo.
There are 35+ hotels available in Tupelo.



