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How to get fromCape Girardeau to Bostonby bus, plane, train, taxi, bus (Greyhound), or car

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There are 6 ways to get from Cape Girardeau to Boston by bus, plane, train, taxi, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly to Laguardia Airport, train

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    11h 16m
    $225–625

  2. Drive  1,191.3 mi

    cheapest
    1. Drive from Cape Girardeau to Bostoncar car 1,191.3 mi
    21h 40m
    $218–314

  3. Taxi, train

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    29h 32m
    $428–902

  4. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Bostonbus bus
    33h 6m
    $224–371

  5. Taxi, bus to Nashville, fly to Theodore Francis Green State Airport, train

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Theodore Francis Green State Airport (PVD)plane plane BNA - PVD
    4. Take the train from TF Green Airport to South Stationtrain train
    11h 35m
    $219–590

  6. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    30h 51m
    $339–806

Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA) flights

Calendar83Weekly Planes
Duration2h 46mAverage Duration
Ticket$137Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Girardeau to Boston.ExpandLaunch map view
  • Distance: 1,256.2 mi
  • Duration: 11h 16m

What companies run services between Cape Girardeau, MO, USA and Boston, MA, USA?

You can take a vehicle from Cape Girardeau to Boston via Cape Girardeau, St Louis Bus Station, Port Authority Bus Terminal, and New York in around 33h 6m.

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