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How to get fromCape Girardeau to Charlestonby bus, plane, taxi, car, or bus (Greyhound)

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There are 6 ways to get from Cape Girardeau to Charleston by bus, plane, taxi, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS)plane plane STL - CHS
    7h 6m
    $129–598

  2. Fly from Cape Girardeau Municipal Airport

    cheapest
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Charleston International Airport (CHS)plane plane CGI - CHS
    8h 6m
    $126–520

  3. Taxi, bus

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    23h 14m
    $247–386

  4. Drive 734.7 mi

    1. Drive from Cape Girardeau to Charlestoncar car 734.7 mi
    13h 22m
    $135–194

  5. Taxi, bus to Nashville, fly

    1. Take the taxi from Cape Girardeau to Carbondale Intermodal Stationtaxi taxi
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Charleston International Airport (CHS)plane plane BNA - CHS
    9h 33m
    $487–1,281

  6. Bus (Greyhound)

    1. Take the bus from Cape Girardeau to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    26h 3m
    $163–317

Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS) flights

Calendar52Weekly Planes
Duration3h 48mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Charleston.ExpandLaunch map view
  • Distance: 849.4 mi
  • Duration: 7h 6m

What companies run services between Cape Girardeau, MO, USA and Charleston, SC, USA?

Corporate Flight Management Inc, American Airlines, and Delta fly from Cape Girardeau Municipal Airport (CGI) to Charleston International Airport (CHS) twice daily. Alternatively, you can take a vehicle from Cape Girardeau to Transit Mall via Cape Girardeau, Memphis Bus Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 26h 3m.

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