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How to get fromCape Girardeau to Chicagoby plane, taxi, train, bus, car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Cape Girardeau to Chicago by plane, taxi, train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cape Girardeau Municipal Airport to Chicago O'Hare International Airport

    best
    1. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    2h 43m
    $121–243

  2. Drive 371.9 mi

    cheapest
    1. Drive from Cape Girardeau to Chicagocar car 371.9 mi
    6h 18m
    $68–98

  3. Taxi, train

    1. Take the taxi from Cape Girardeau to Carbondaletaxi taxi
    2. Take the train from Carbondale to Chicago Union Stationtrain train Saluki / ...
    6h 30m
    $203–332

  4. Taxi, bus

    1. Take the taxi from Cape Girardeau to Anna - Shelltaxi taxi
    2. Take the bus from Anna - Shell to Chicagobus bus Querétaro
    8h
    $147–274

  5. Taxi to Williamson County Regional Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Cape Girardeau to Williamson County Regional Airport (MWA)taxi taxi
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    3h 37m
    $220–382

  6. Taxi to Barkley Regional Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Cape Girardeau to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    3h 43m
    $185–424

  7. Bus to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    5h 24m
    $102–426

  8. Bus to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    5h 47m
    $317–766

  9. Bus, train

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    7h 49m
    $132–248

  10. Bus

    1. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    8h 59m
    $92–143

Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD) flights

Calendar7Weekly Planes
Duration1h 45mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Cape Girardeau to Chicago.ExpandLaunch map view
  • Distance: 365.4 mi
  • Duration: 2h 43m

What companies run services between Cape Girardeau, MO, USA and Chicago, IL, USA?

Corporate Flight Management Inc flies from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD) once daily. Alternatively, you can take a vehicle from Cape Girardeau to Chicago Bus Station via Cape Girardeau and St Louis Bus Station in around 8h 59m.

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